Query: NC_009515:307800 Methanobrevibacter smithii ATCC 35061, complete genome
Lineage: Methanobrevibacter smithii; Methanobrevibacter; Methanobacteriaceae; Methanobacteriales; Euryarchaeota; Archaea
General Information: Methanobrevibacter smithii ATCC 35061 (DSM 861) (strain PS) was isolated from a sewage digester in Gainesville, Florida, USA. Sewage digester isolate. Human gut methanogen. Methanobrevibacter smithii can be isolated from anoxic environments such as anaerobic digesters, anaerobic soil and sediment, and the gastrointestinal tracts of humans, ruminants and other animals. This organism is the dominant archaeal symbiont found in the human gut.
Subject: NC_006511:3364448 Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCC
Lineage: Salmonella enterica; Salmonella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria
General Information: This serovar has a narrow host range and causes a typhoid-like (paratyphoid fever) illness in humans. It is especially prevalent in southern and eastern Asia, and has been associated with some particularly virulent outbreaks. A number of isolates are increasingly antibiotic resistant. Causes enteric infections. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis, from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.