Query: NC_009441:3562125 Flavobacterium johnsoniae UW101 chromosome, complete genome
Lineage: Flavobacterium johnsoniae; Flavobacterium; Flavobacteriaceae; Flavobacteriales; Bacteroidetes; Bacteria
General Information: Flavobacterium johnsoniae ATCC 17061 was isolated from soil in England. Common soil and freshwater bacterium that is motile by gliding. Flavobacterium johnsoniae, formerly Cytophaga johnsonae, is common in soil and freshwater. This organism belongs to a large group of related environmental microorganisms that are characterized by the ability to utilize a wide variety of naturally occurring complex compounds, such as chitin, cellulose, and lignin.
Subject: NC_010729:619664 Porphyromonas gingivalis ATCC 33277, complete genome
Lineage: Porphyromonas gingivalis; Porphyromonas; Porphyromonadaceae; Bacteroidales; Bacteroidetes; Bacteria
General Information: This strain was isolated from human gingiva. This organism is associated with severe and chronic periodontal (tissues surrounding and supporting the tooth) diseases. Progression of the disease is caused by colonization by this organism in an anaerobic environment in host tissues and severe progression results in loss of the tissues supporting the tooth and eventually loss of the tooth itself. The black pigmentation characteristic of this bacterium comes from iron acquisition that does not use the typical siderophore system of other bacteria but accumulates hemin. Peptides appear to be the predominant carbon and energy source of this organism, perhaps in keeping with its ability to destroy host tissue. Oxygen tolerance systems play a part in establishment of the organism in the oral cavity, including a superoxide dismutase. Pathogenic factors include extracellular adhesins that mediate interactions with other bacteria as well as the extracellular matrix, and a host of degradative enzymes that are responsible for tissue degradation and spread of the organism including the gingipains, which are trypsin-like cysteine proteases.