Pre_GI Gene

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Host: NC_010729 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_010729:619664 Porphyromonas gingivalis ATCC 33277, complete genome

Host Lineage: Porphyromonas gingivalis; Porphyromonas; Porphyromonadaceae; Bacteroidales; Bacteroidetes; Bacteria

General Information: This strain was isolated from human gingiva. This organism is associated with severe and chronic periodontal (tissues surrounding and supporting the tooth) diseases. Progression of the disease is caused by colonization by this organism in an anaerobic environment in host tissues and severe progression results in loss of the tissues supporting the tooth and eventually loss of the tooth itself. The black pigmentation characteristic of this bacterium comes from iron acquisition that does not use the typical siderophore system of other bacteria but accumulates hemin. Peptides appear to be the predominant carbon and energy source of this organism, perhaps in keeping with its ability to destroy host tissue. Oxygen tolerance systems play a part in establishment of the organism in the oral cavity, including a superoxide dismutase. Pathogenic factors include extracellular adhesins that mediate interactions with other bacteria as well as the extracellular matrix, and a host of degradative enzymes that are responsible for tissue degradation and spread of the organism including the gingipains, which are trypsin-like cysteine proteases.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
619664620440777putative tRNA pseudouridine synthase BQuickGO ontologyBLASTP
620450621292843putative undecaprenol kinaseQuickGO ontologyBLASTP
621400621627228hypothetical proteinBLASTP
621674622561888putative cell division protein FtsXQuickGO ontologyBLASTP
624175624516342hypothetical proteinBLASTP
6246886257491062transposase in ISPg1QuickGO ontologyBLASTP
625842625943102hypothetical proteinBLASTP
62604562612985tRNA-SerQuickGO ontologyBLASTP
6267326278171086transposase in ISPg1QuickGO ontologyBLASTP
627916628137222conserved hypothetical protein found in conjugate transposonQuickGO ontologyBLASTP
6281596292651107hypothetical proteinBLASTP
6293536349655613hypothetical protein
6351516366351485hypothetical proteinBLASTP
6367316388122082DNA topoisomerase IQuickGO ontologyBLASTP
6389546405941641hypothetical proteinBLASTP
6408696421971329hypothetical proteinBLASTP
642231643133903transposase in ISPg3QuickGO ontologyBLASTP
643172643486315hypothetical protein
6435706446551086transposase in ISPg1QuickGO ontologyBLASTP
644756645304549hypothetical proteinBLASTP
645609645830222hypothetical proteinBLASTP
6460476471051059putative Fic family proteinQuickGO ontologyBLASTP
6471366485181383hypothetical proteinBLASTP
648638649075438putative conserved protein found in conjugate transposon TraQQuickGO ontologyBLASTP
649095649679585putative conserved protein found in conjugate transposon TraOQuickGO ontologyBLASTP
649684650619936conserved protein found in conjugate transposon TraNQuickGO ontologyBLASTP
6506936520541362putative conserved protein found in conjugate transposon TraMQuickGO ontologyBLASTP
652051652314264conserved hypothetical protein found in conjugate transposonQuickGO ontology
652318652941624putative conserved protein found in conjugate transposon TraKQuickGO ontologyBLASTP
652959653945987conserved transmembrane protein found in conjugate transposon TraJQuickGO ontologyBLASTP
653966654589624putative conserved protein found in conjugate transposon TraIQuickGO ontologyBLASTP
654641655108468hypothetical proteinBLASTP