Query: NC_008343:1548020 Granulibacter bethesdensis CGDNIH1, complete genome
Lineage: Granulibacter bethesdensis; Granulibacter; Acetobacteraceae; Rhodospirillales; Proteobacteria; Bacteria
General Information: Isolated from a patient with fever and lymphadenitis. Chronic granulomatous disease (CGD) is a rare inherited disease of the phagocyte NADPH oxidase system causing defective production of toxic oxygen metabolites, impaired bacterial and fungal killing, and recurrent life-threatening infections. This species was isolated from a 39 year old man with CGD and was shown to be the causal agent of the disease by classical methods. The isolation of this organism is the first known case of a bacterium from the Acetobacteraceae family to be the cause of an invasive human disease.
Subject: NC_014313:2059933 Hyphomicrobium denitrificans ATCC 51888 chromosome, complete
Lineage: Hyphomicrobium denitrificans; Hyphomicrobium; Hyphomicrobiaceae; Rhizobiales; Proteobacteria; Bacteria
General Information: Environment: Fresh water; Temp: Mesophile. An aerobic, motile Gram-negative bacterium. Hyphomicrobium denitrificans has a biphasic life style, which consists of a motile phase of flagellated swarmer cells, and a cessile phase in which a long prosthecate is produced at one end of the bacteria through which budding cells emerge. Newly budded cells in turn produce flagella and go through a motile phase and the cycle continues. These organisms can colonize the surfaces of marine environments which enables additional species to colonize at later stages. This organism is also able to utilize methanol as a sole source of energy.