Query: NC_008011:213386 Lawsonia intracellularis PHE/MN1-00, complete genome Lineage: Lawsonia intracellularis; Lawsonia; Desulfovibrionaceae; Desulfovibrionales; Proteobacteria; Bacteria General Information: Lawsonia intracellularis PHE/MN1-00 was isolated from intestinal mucosal lesions in pigs that had proliferative enteropathy (PE). When introduced into health pigs, this organism produced the clinical and histological signs of PE. Causative agent for proliferative enteropathy in swine. This organism causes proliferative enteropathy (ileitis) in swine and other domesticated animals resulting in severe losses each year. This obligate intracellular pathogen infects the mucosa of the lower intestinal tract by initially infecting crypt cells, which are precursors that normally grow and divide in order to replace the epithelial cells. Once infection occurs, the crypt cells are stimulated to grow and divide abnormally, resulting in the proliferative phenotype. In severe cases of the disease the entire bowel can become affected and persist for up to 40 days, greatly affecting the host animal.
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General Information: Use in fermentation of food products. A distinctive characteristic of pediococci is their ability to form tetrads via cell division in two perpendicular directions in a single plane. Like other lactic acid bacteria, species of Pediococcus are acid tolerant, cannot synthesize porphyrins, and possess a strictly fermentative (homofermentative) facultatively anaerobic metabolism with lactic acid as the major metabolic end product. They also occur in such food products as cured meat, raw sausages, and marinated fish, and are are used for biotechnological processing and preservation of foods. This bacterium can be isolated from a variety of plant materials and bacterial-ripened cheeses. This organism is used as an acid producing starter culture in the fermentation of some sausages, cucumbers, green beans, soy milk, and silage. Some strains have been reported to contain several (3-5) resident plasmids that render the bacterium capable of fermenting some sugars (raffinose, melibiose, and sucrose), as well as producing bacteriocins.