Query: NC_007761:3962474 Rhizobium etli CFN 42, complete genome
Lineage: Rhizobium etli; Rhizobium; Rhizobiaceae; Rhizobiales; Proteobacteria; Bacteria
General Information: It is a nitrogen-fixing symbiotic bacteria that interacts with the root of the common bean plant Phaseolus vulgaris. P. etli and its relation to other nitrogen/fixing symbionts has been well studied. The genomic sequence will provide information on the process of symbiosis, on the genetic systems that allow the survival and adaptations of this bacteria to the soil, and on the evolutionary relationship and the symbiosis origin of this organism.
Subject: NC_006085:1379370 Propionibacterium acnes KPA171202, complete genome
Lineage: Propionibacterium acnes; Propionibacterium; Propionibacteriaceae; Actinomycetales; Actinobacteria; Bacteria
General Information: Isolated from human skin. Acne causing bacterium. This bacterium is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic.It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline. Some other forms of therapy include chemicals that enhance skin removal or slow the production of sebum.