Pre_GI Gene

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Host: NC_006085 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_006085:1379370 Propionibacterium acnes KPA171202, complete genome

Host Lineage: Propionibacterium acnes; Propionibacterium; Propionibacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Isolated from human skin. Acne causing bacterium. This bacterium is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic.It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline. Some other forms of therapy include chemicals that enhance skin removal or slow the production of sebum.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
137937013806231254D-3-phosphoglycerate dehydrogenaseQuickGO ontologyBLASTP
13806071381392786dipeptide ABC transporter ATP-bindingQuickGO ontologyBLASTP
13813921382201810putative ATP-binding ABC transporter proteinQuickGO ontologyBLASTP
13822011383013813permease protein of oligopeptide ABC transporterQuickGO ontologyBLASTP
13830101383987978ABC transporter permease proteinQuickGO ontologyBLASTP
138398413854711488ABC transporter substrate binding proteinQuickGO ontologyBLASTP
13861641386718555hypothetical protein
13873571387752396hypothetical protein
13880981388511414hypothetical proteinBLASTP
13887121388969258hypothetical proteinBLASTP
13889661389631666plasmid partition protein ParAQuickGO ontologyBLASTP
13899061390727822hypothetical proteinBLASTP
13908841391147264hypothetical protein
13911401391379240hypothetical proteinBLASTP
139202713932471221hypothetical proteinBLASTP
139383613951431308conserved protein putative biotin carboxylaseQuickGO ontologyBLASTP
13951301395843714putative thioesteraseQuickGO ontologyBLASTP
139584013975791740non-ribosomal peptide synthetaseQuickGO ontologyBLASTP
139760214008983297surfactin synthetase subunit 1QuickGO ontologyBLASTP
14009061401895990cysteine synthaseornithine cyclodeaminaseQuickGO ontologyBLASTP
140189614028971002cystathionine beta-synthaseQuickGO ontologyBLASTP