Query: NC_007298:1418500 Dechloromonas aromatica RCB, complete genome
Lineage: Dechloromonas aromatica; Dechloromonas; Rhodocyclaceae; Rhodocyclales; Proteobacteria; Bacteria
General Information: This strain was enriched as a hydrocarbon-oxidizing chlorate-reducer from the Potomac River, Maryland, USA. This organism is the first one to have the capability of benzene oxidation in pure anaerobic culture by coupling it to nitrate reduction which is of importance due to the anaerobic environments often found in bioremediation projects. It can reduce perchlorate and chlorate to chloride. This organism may be used for bioremediation as it can oxidize aromatic hydrocarbon compounds, including benzene, in the absence of oxygen. Benzene is an important pollutant, and is used in many manufacturing processes and is a component of diesel fuel.
Subject: NC_004917:946550 Helicobacter hepaticus ATCC 51449, complete genome
Lineage: Helicobacter hepaticus; Helicobacter; Helicobacteraceae; Campylobacterales; Proteobacteria; Bacteria
General Information: This organism was found to be linked to an increasing incidence of liver tumors in mouse colonies at the National Cancer Institute in 1992. Normally it resides in the lower intestines, but it can cause chronic hepatitis. This organism has a similar urease gene cluster and cytolethal distending toxin as compared to Helicobacter pylori, but lacks other virulence factors such as the vacuolating cytotoxin and the cag pathogenicity island. However, it does contain a pathogenicity island that encodes proteins similar to those found in a type IV secretion system. Causes liver disease. This genus consists of organisms that colonize the mucosal layer of the gastrointestinal tract or are found enterohepatically (in the liver). This species was associated with an increase in liver tumors. It can cause active chronic hepatitis and typhlitis (inflammation of a region at the beginning of the large intestine), hepatocellular tumors, and gastric bowel disease in various mice strains.