Query: NC_006138:1245944 Desulfotalea psychrophila LSv54, complete genome Lineage: Desulfotalea psychrophila; Desulfotalea; Desulfobulbaceae; Desulfobacterales; Proteobacteria; Bacteria General Information: This organism was isolated from marine sediments off of the coast of Svalbard, and can grow at temperatures as low as -1.7 degrees C. Sulfate-reducing bacterium. This organism grows on more complex organic compounds such as acetate, propionate, butyrate, lactate as well as by using simpler compounds such as hydrogen. This organism is an important part of global biogeochemical cycling of carbon and other nutrients.
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General Information: This strain was isolated from a case of relapsing fever in western Washington, USA. Borrelia hermsii is the causative agent of tick-borne relapsing fever in the western United States and Canada. Borrelia then multiplies rapidly, causing a generalized infection throughout the tick. While feeding, the tick passes the organism into a mammalian host through its infectious saliva. Relapsing fever is characterized by a period of chills, fever, headache, and malaise, an asymptomatic period, followed by another episode of symptoms. This cycle of relapsing is due to changes in the surface proteins of Borrelia, which allow it to avoid detection and removal by the host immune system. This antigenic variation is the result of homologous recombination of silent proteins into an expressed locus, causing partial or complete replacement of one serotype with another. These plasmids carry genes involved in antigenic variation and pathogenicity.