Pre_GI: SWBIT SVG BLASTP

Query: NC_003552:4782635 Methanosarcina acetivorans C2A, complete genome

Lineage: Methanosarcina acetivorans; Methanosarcina; Methanosarcinaceae; Methanosarcinales; Euryarchaeota; Archaea

General Information: This wild-type strain (C2A; DSM2834) is the type strain of this species and was isolated from marine sediment. Anaerobic methane-producing archeon. This organism is a strictly anaerobic, nonmotile, methane-producing Archaea responsible for virtually all biogenic methane production, a process of critical importance as a key step in the global carbon cycle. This process results in the production of significant amounts of greenhouse gas. This organism is also important in production of alternative fuels and plays a role in both agricultural and waste treatment industry. Optimal growth occurs at pH 6.5-7.0.

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Subject: NC_009012:1901492 Clostridium thermocellum ATCC 27405, complete genome

Lineage: Clostridium thermocellum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This strain is a well studied producer of endoglucanase and several restriction endonucleases. Thermophilic cellulose degrading bacterium. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. Some species are capable of producing organic solvents (acetone, ethanol, etc,), molecular hydrogen and other useful compounds. This organism is a thermophilic anaerobe that produces an extracellular enzyme system capable of degrading crystalline cellulose to soluble sugars that are further utilized as the carbon source for growth.