Query: NC_002488:2502000 Xylella fastidiosa 9a5c, complete genome Lineage: Xylella fastidiosa; Xylella; Xanthomonadaceae; Xanthomonadales; Proteobacteria; Bacteria General Information: This strain was derived from a pathogenic strain (8.1b) isolated in 1992 in France that had come from infected twigs derived from the sweet orange strain Valencia in Brazil in the same year. This organism was first identified in 1993 as the causal agent of citrus variegated chlorosis, a disease that affects varieties of sweet oranges. Other strains of this species cause a range of diseases in mulberry, pear, almond, elm, sycamore, oak, maple, pecan and coffee which collectively result in multimillion dollar devastation of economically important plants. Xylella fastidiosa is similar to Xanthomonas campestris pv. campestris in that it produces a wide variety of pathogenic factors for colonization in a host-specific manner including a large number of fimbrial and afimbrial adhesins for attachment. It does not contain a type III secretion system, but possesses genes for a type II secretion system for export of exoenzymes that degrade the plant cell wall and allow the bacterium to colonize the plant xylem.
- Sequence; - BLASTP hit: hover for score (Low score = Light, High score = Dark); - hypothetical protein; - cds: hover for description
General Information: This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, is composed of obligate intracellular pathogens. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host. Rickettsia typhi causes murine typhus and is an obligate intracellular pathogen that infects both the flea vector and hosts such as human, rat, and mouse. In the flea vector, the bacterium penetrates the gut epithelial barrier and is found in the feces which become infective.