Query: NC_016603:3259432 Acinetobacter calcoaceticus PHEA-2 chromosome, complete genome
Lineage: Acinetobacter calcoaceticus; Acinetobacter; Moraxellaceae; Pseudomonadales; Proteobacteria; Bacteria
General Information: Acinetobacter calcoaceticus is part of the normal flora of the human skin and throat. It is an opportunistic pathogen. Originally isolated from industrial wastewater in China because of its ability to use phenol as the sole carbon source.
Subject: NC_007797:914500 Anaplasma phagocytophilum HZ, complete genome
Lineage: Anaplasma phagocytophilum; Anaplasma; Anaplasmataceae; Rickettsiales; Proteobacteria; Bacteria
General Information: Isolated from a patient in New York, USA, in 1995. This organism is a tick-borne (Ixodesspp.) obligate intracellular pathogen that infects humans and causes human granulocytic anaplasmosis as well as infecting several other types of animals. This organism produces a number of pathogenic factors that aid virulence. These include specific adhesins for neutrophils, virulence factors that inhibit both phagosome-lysozome fusion and production of reactive oxygen species that would normally kill the bacterium. The bacterium also inhibits programmed cell death of the neutrophil (apoptosis) and induces expression of interleukin-8, which causes neutrophil chemotaxis, thereby increasing the spread of the bacterium throughout the host organism.