Query: NC_016024:156000 Candidatus Chloracidobacterium thermophilum B chromosome chromosome Lineage: Chloracidobacterium thermophilum; Chloracidobacterium; Acidobacteriaceae; ; Acidobacteria; Bacteria General Information: This organism produces bacteriochlorophyll a and c under oxic conditions and represents a new group of photosynthetic bacteria. The only known chlorophototroph in the phylum Acidobacteria. Aerobic photoheterotroph that lacks the ability to synthesize several essential nutrients. Naturally inhabits microbial mats of alkaline siliceous hot springs in Yellowstone National Park.
- Sequence; - BLASTN hit (Low score = Light, High score = Dark) - hypothetical protein; - cds: hover for description
General Information: Isolated from a patient in New York, USA, in 1995. This organism is a tick-borne (Ixodesspp.) obligate intracellular pathogen that infects humans and causes human granulocytic anaplasmosis as well as infecting several other types of animals. This organism produces a number of pathogenic factors that aid virulence. These include specific adhesins for neutrophils, virulence factors that inhibit both phagosome-lysozome fusion and production of reactive oxygen species that would normally kill the bacterium. The bacterium also inhibits programmed cell death of the neutrophil (apoptosis) and induces expression of interleukin-8, which causes neutrophil chemotaxis, thereby increasing the spread of the bacterium throughout the host organism.