Pre_GI: SWBIT SVG BLASTN

Query: NC_015697:33665 Lactobacillus reuteri SD2112 chromosome, complete genome

Lineage: Lactobacillus reuteri; Lactobacillus; Lactobacillaceae; Lactobacillales; Firmicutes; Bacteria

General Information: Lactobacillus reuteri is a member of the normal microbial community of the gut in humans and animals. This organism produces antibiotic compounds, such as reutericin and reuterin, which have inhibitory effects on pathogenic microorganisms. In addition, Lactobacillus reuteri is commonly used as a probiotic to maintain the balance of the gut microbial flora and stimulate the intestinal immune system.

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Subject: NC_010067:4149298 Salmonella enterica subsp. arizonae serovar 62:z4,z23:--, complete

Lineage: Salmonella enterica; Salmonella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This subspecies (IIIa) is usually found associated with reptiles, although contact with infected animals can result in the spread of the organism to humans or animals such as turkeys. This strain was originally isolated from a cornsnake in 1986 in Oregon, USA. Causes enteric infections. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis, from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.