Query: NC_015275:3846260 Clostridium lentocellum DSM 5427 chromosome, complete genome Lineage: Cellulosilyticum lentocellum; Cellulosilyticum; Lachnospiraceae; Clostridiales; Firmicutes; Bacteria General Information: Isolation: River sediment with paper mill waste; Temp: Mesophile; Temp: 40C; Isolation:river sediment with paper mill waste; Country:United Kingdom: River Don, Scotland. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. This is a cellulolytic bacterium isolated from river sediment containing paper-mill waste.
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General Information: This strain is a variant of the L2 serovar. Serovar L2 strains are associated with sexually transmitted infections and cause lymphogranuloma vernerum, a systemic infection involving the lymph nodes. Chlamydia trachomatis L2b/UCH-1/proctitis was isolated from a recent outbreak of proctitis in Europe. Causes disease in either the eye or the urogenital tract. Bacteria belonging to the Chlamydiales group are obligate intracellular parasites of eukaryotic cells. They are found within vertebrates, invertebrate cells, and amoebae hosts. Chlamydiae are one of the commonest causes of sexually transmitted diseases (STDs) and if left untreated may cause infertility in women. They are transmitted by direct contact or aerosols, and can cause various diseases, while also being able to coexist with the host in an apparently asymptomatic state. Chlamydia trachomatis causes infection that leads to blindness and sexually transmitted diseases in humans. There are 15 serovariants that preferentially cause disease in either the eye or the urogenital tract. The trachoma (infection of the mucous membrane of the eyelids) biovars are noninvasive and can cause blinding trachoma (variants A, B, Ba, and C), or sexually transmitted diseases (variants, D, E, F, G, H, I, J, and K). The lymphogranuloma venereum biovars (variants L1, L2, and L3) can cross the epithelial cells of mucous membranes and then travel through the lymphatic system where they multiply within mononuclear phagocytes found within the lymph nodes.