Query: NC_014831:65408 Thermaerobacter marianensis DSM 12885 chromosome, complete genome
Lineage: Thermaerobacter marianensis; Thermaerobacter; Clostridiales Family XVII; Clostridiales; Firmicutes; Bacteria
General Information: Country: Pacific Ocean; Environment: Mud; Isolation: mud from the Challenger Deep in the Mariana; Hyperthermophile; Temp: 74-76C. Thermaerobacter marianensis was isolated from mud from the Mariana Trench in the Pacific Ocean at a depth of >10000 meters.
Subject: NC_008767:1888950 Neisseria meningitidis FAM18, complete genome
Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria
General Information: Isolated from a patient with meningococcal septicemia. Causes septicemia and meningitis. The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.