Query: NC_014762:2428721 Sulfuricurvum kujiense DSM 16994 chromosome, complete genome
Lineage: Sulfuricurvum kujiense; Sulfuricurvum; Helicobacteraceae; Campylobacterales; Proteobacteria; Bacteria
General Information: Country: Japan; Isolation: Drain water from an underground crude-oil; Temp: Mesophile; Temp: 25C. This is a facultatively anaerobic, chemolithoautotrophic, sulfur-oxidizing bacterium, isolated from an underground crude-oil storage cavity at Kuji in Iwate, Japan.
Subject: NC_007797:914500 Anaplasma phagocytophilum HZ, complete genome
Lineage: Anaplasma phagocytophilum; Anaplasma; Anaplasmataceae; Rickettsiales; Proteobacteria; Bacteria
General Information: Isolated from a patient in New York, USA, in 1995. This organism is a tick-borne (Ixodesspp.) obligate intracellular pathogen that infects humans and causes human granulocytic anaplasmosis as well as infecting several other types of animals. This organism produces a number of pathogenic factors that aid virulence. These include specific adhesins for neutrophils, virulence factors that inhibit both phagosome-lysozome fusion and production of reactive oxygen species that would normally kill the bacterium. The bacterium also inhibits programmed cell death of the neutrophil (apoptosis) and induces expression of interleukin-8, which causes neutrophil chemotaxis, thereby increasing the spread of the bacterium throughout the host organism.