Pre_GI: SWBIT SVG BLASTN

Query: NC_014032:338547 Salinibacter ruber M8 chromosome, complete genome

Lineage: Salinibacter ruber; Salinibacter; Rhodothermaceae; Bacteroidetes Order II; Bacteroidetes; Bacteria

General Information: Salinibacter ruber (strain M8) is a brightly red-pigmented, motile, rod-shaped, extremely halophilic Gram-negative bacterium isolated from a saltern crystallizer pond in Mallorca, Spain. It grows optimally at salt concentrations between 20 and 30% and does not grow below 15% salt. S. ruber is among the most halophilic organisms known within the domain Bacteria. This organism is an extremely halophilic aerobe originally isolated from saltern crystallizer ponds in Spain. These bacteria can coexist in significant colonies with halophilic archaea under saline conditions. In contrast to other bacteria they do not regulate their intracellular salt conditions through proton pumps, but instead their protein makeup has adapted to be functional under high ionic conditions.

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BLASTN Alignment.txt

Subject: NC_014039:499233 Propionibacterium acnes SK137 chromosome, complete genome

Lineage: Propionibacterium acnes; Propionibacterium; Propionibacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This bacterium is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline.