Query: NC_011565:620801 Candidatus Azobacteroides pseudotrichonymphae genomovar. CFP2,
Lineage: Azobacteroides pseudotrichonymphae; Azobacteroides; ; Bacteroidales; Bacteroidetes; Bacteria
General Information: Candidatus Azobacteroides pseudotrichonymphae genomovar. CFP2 was isolated from a single cell of the protist Pseudotrichonympha grassii which resides in the termite gut. Gram-negative bacteria that are specifically found within the cytoplasm of the parabasalid protist Pseudotrichonympha grassii which resides in the hindgut of the termite Coptotermes formosanus. Candidatus Azobacteroides pseudotrichonymphae may be involved in providing nitrogen compounds for the host.
Subject: NC_007797:914500 Anaplasma phagocytophilum HZ, complete genome
Lineage: Anaplasma phagocytophilum; Anaplasma; Anaplasmataceae; Rickettsiales; Proteobacteria; Bacteria
General Information: Isolated from a patient in New York, USA, in 1995. This organism is a tick-borne (Ixodesspp.) obligate intracellular pathogen that infects humans and causes human granulocytic anaplasmosis as well as infecting several other types of animals. This organism produces a number of pathogenic factors that aid virulence. These include specific adhesins for neutrophils, virulence factors that inhibit both phagosome-lysozome fusion and production of reactive oxygen species that would normally kill the bacterium. The bacterium also inhibits programmed cell death of the neutrophil (apoptosis) and induces expression of interleukin-8, which causes neutrophil chemotaxis, thereby increasing the spread of the bacterium throughout the host organism.