Query: NC_010830:475248 Candidatus Amoebophilus asiaticus 5a2, complete genome
Lineage: Amoebophilus asiaticus; Amoebophilus; Amoebophilaceae; Cytophagales; Bacteroidetes; Bacteria
General Information: Candidatus Amoebophilus asiaticus 5a2 is an obligate endosymbiont found in Acanthamoeba sp. TUMSJ-321. This organism is a member of the highly diverse bacterial phylum Bacteroidetes which includes the endosymbiont lineages represented by the sister taxa Candidatus A. asiaticus and Candidatus Cardinium hertigii, a symbiont of arthropods.
Subject: NC_012808:420334 Methylobacterium extorquens AM1, complete genome
Lineage: Methylobacterium extorquens; Methylobacterium; Methylobacteriaceae; Rhizobiales; Proteobacteria; Bacteria
General Information: First isolated in 1960 in Oxford, England, as an airborne contaminant growing on methylamine. This strain can grow on methylamine or methanol, but not methane. This organism is capable of growth on one-carbon compounds such as methanol. Methanol is oxidized to formaldehyde which is then used metabolically to generate either energy or biomass. These bacteria are commonly found in the environment, especially associated with plants which produce methanol when metabolizing pectin during cell wall synthesis. At least 25 genes are required for this complex process of converting methanol to formaldehyde and this specialized metabolic pathway is of great interest.