Query: NC_010003:570643 Petrotoga mobilis SJ95, complete genome Lineage: Petrotoga mobilis; Petrotoga; Thermotogaceae; Thermotogales; Thermotogae; Bacteria General Information: Petrotoga mobilis SJ95 (DSM 10674) is an anaerobic thermophile, isolated from the production waters of a North Sea oil reservoir. This organism, a member of the Thermotogales, has the characteristic morphology of one or more cells contained in a sheath-like envelope which extends beyond the cell wall. Petroleum reservoirs are a unique subsurface environment characterized by high temperatures, moderate to high salt concentrations, and abundant organic matter.
- Sequence; - BLASTN hit (Low score = Light, High score = Dark) - hypothetical protein; - cds: hover for description
General Information: This strain was isolated from human gingiva. This organism is associated with severe and chronic periodontal (tissues surrounding and supporting the tooth) diseases. Progression of the disease is caused by colonization by this organism in an anaerobic environment in host tissues and severe progression results in loss of the tissues supporting the tooth and eventually loss of the tooth itself. The black pigmentation characteristic of this bacterium comes from iron acquisition that does not use the typical siderophore system of other bacteria but accumulates hemin. Peptides appear to be the predominant carbon and energy source of this organism, perhaps in keeping with its ability to destroy host tissue. Oxygen tolerance systems play a part in establishment of the organism in the oral cavity, including a superoxide dismutase. Pathogenic factors include extracellular adhesins that mediate interactions with other bacteria as well as the extracellular matrix, and a host of degradative enzymes that are responsible for tissue degradation and spread of the organism including the gingipains, which are trypsin-like cysteine proteases.