Pre_GI Gene

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Host: NC_010729 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_010729:225616 Porphyromonas gingivalis ATCC 33277, complete genome

Host Lineage: Porphyromonas gingivalis; Porphyromonas; Porphyromonadaceae; Bacteroidales; Bacteroidetes; Bacteria

General Information: This strain was isolated from human gingiva. This organism is associated with severe and chronic periodontal (tissues surrounding and supporting the tooth) diseases. Progression of the disease is caused by colonization by this organism in an anaerobic environment in host tissues and severe progression results in loss of the tissues supporting the tooth and eventually loss of the tooth itself. The black pigmentation characteristic of this bacterium comes from iron acquisition that does not use the typical siderophore system of other bacteria but accumulates hemin. Peptides appear to be the predominant carbon and energy source of this organism, perhaps in keeping with its ability to destroy host tissue. Oxygen tolerance systems play a part in establishment of the organism in the oral cavity, including a superoxide dismutase. Pathogenic factors include extracellular adhesins that mediate interactions with other bacteria as well as the extracellular matrix, and a host of degradative enzymes that are responsible for tissue degradation and spread of the organism including the gingipains, which are trypsin-like cysteine proteases.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
2256162267881173hypothetical proteinBLASTP
2269422280271086transposase in ISPg1QuickGO ontologyBLASTP
228170228556387hypothetical proteinBLASTP
228667228975309hypothetical proteinBLASTP
228974229342369hypothetical proteinBLASTP
229311230785147516S ribosomal RNAQuickGO ontologyBLASTP
230898231056159hypothetical proteinBLASTP
231183231338156hypothetical protein
23134823142174tRNA-IleQuickGO ontologyBLASTP
23142323149977tRNA-AlaQuickGO ontology
231618234450283323S ribosomal RNAQuickGO ontologyBLASTP
2345972347041085S ribosomal RNAQuickGO ontologyBLASTP
2351102361951086transposase in ISPg1QuickGO ontologyBLASTP
236434237003570partial transposase in ISPg1QuickGO ontologyBLASTP
237092237517426partial transposase in ISPg1QuickGO ontologyBLASTP
2378862400182133DNA topoisomerase IIIQuickGO ontologyBLASTP
240698240988291hypothetical proteinBLASTP
2414042425101107glycosyl transferase family 4QuickGO ontologyBLASTP
2427582439661209UDP-N-acetyl-D-mannosaminuronic acid dehydrogenaseQuickGO ontologyBLASTP
244252245238987probable glycosyltransferaseQuickGO ontologyBLASTP