Query: NC_009848:1542978 Bacillus pumilus SAFR-032, complete genome
Lineage: Bacillus pumilus; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria
General Information: Bacillus pumilus SAFR-032 was isolated from the Spacecraft Assembly Facility at NASA Jet Propulsion Laboratory, USA and produces spores highly resistant to UV radiation. A ubiquitous soil organism. Bacillus pumilus is a naturally occurring, ubiquitous soil microorganism. Commonly found in a variety of food commodities, some strains have developed an increased tolerance to gamma irradiation. This bacterium colonizes the root zone of some plants, where it inhibits soil-borne fungal diseases and nematodes. It is also undergoing evaluation for commercial production of cellulase, an enzyme used for conversion of cellulolytic materials to soluble sugars or solvents.
Subject: NC_008767:927810 Neisseria meningitidis FAM18, complete genome
Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria
General Information: Isolated from a patient with meningococcal septicemia. Causes septicemia and meningitis. The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.