Query: NC_009445:6621996 Bradyrhizobium sp. ORS 278 chromosome, complete genome Lineage: Bradyrhizobium; Bradyrhizobium; Bradyrhizobiaceae; Rhizobiales; Proteobacteria; Bacteria General Information: This strain was isolated from an Aeschynomene stem nodule and is photosynthetic, which is a rare trait in Rhizobium bacteria. These strains exhibit a photoheterotrophic and strictly aerobic photosynthesis. In culture, most stem isolates show the same pink coloration, while a few strains produce orange pigmentation. Pigment analyses showed that bacteriochlorophyll and spirilloxanthin, two pigments of the light harvesting system, are common to all of these photosynthetic Bradyrhizobium strains, whereas orange strains produce an additional bicyclic carotenoid, canthaxanthin (4,4'-diketo-beta-carotene). Bradyrhizobium sp. strain ORS278 produces the highest quantity of canthaxanthin of all tested photosynthetic bacteria; canthaxanthin represents 85% of its total carotenoid content.
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General Information: This strain was probably isolated from salmon eggs associated with a foodborne case of botulism in Alaska, however the exact details are not available. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.