Query: NC_009009:1876367 Streptococcus sanguinis SK36, complete genome Lineage: Streptococcus sanguinis; Streptococcus; Streptococcaceae; Lactobacillales; Firmicutes; Bacteria General Information: This strain was isolated from human dental plaque in 1980 and is virulent in a rat model. Indigenous oral bacteria that causes dental decay and possibly endocarditis. Most streptococci are facultative anaerobes, and some are obligate anaerobes. Serologic grouping is based on antigenic differences in cell wall carbohydrates, in cell wall pili-associated protein, and in the polysaccharide capsule in group B streptococci. This microbe is found associated with human oral bacterial communities and can colonize the dental surfaces, aiding other organisms in attachment. Progression of caries and periodontal disease are associated with this microbe as is endocarditis which can lead to death.
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General Information: This is a Biotype 1 hospital isolate from Taiwan. It contains larger chromosomes and >1000 genes as compared to Vibrio cholerae and contains a conjugative plasmid, pYJ016. There are numerous virulence factors including a cytolysin, protease, capsular polysaccharide as well as iron-uptake systems encoded in the genome. This genus is abundant in marine or freshwater environments such as estuaries, brackish ponds, or coastal areas; regions that provide an important reservoir for the organism in between outbreaks of the disease. Vibrio can affect shellfish, finfish, and other marine animals and a number of species are pathogenic for humans. Organisms of this species are opportunistic pathogens that can attack immunocompromised patients and causes gastroenteritis (inflammation of mucous membranes of stomach and intestine), wound infections, and primary septicemia (spread of the organism through the blood). This organism is the major cause of death from eating raw oysters, especially in people with liver damage. It only affects humans and other primates.