Query: NC_006156:389152 Borrelia garinii PBi chromosome linear, complete sequence
Lineage: Borrelia bavariensis; Borrelia; Spirochaetaceae; Spirochaetales; Spirochaetes; Bacteria
General Information: This strain (OspA serotype 4) was isolated in Germany from the cerebrospinal fluid of a patient with neuroborreliosis. This is a spirochete causing Lyme borreliosis. It is transmitted by rodents. Human pathogen.
Subject: NC_009879:141000 Rickettsia canadensis str. McKiel, complete genome
Lineage: Rickettsia canadensis; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria
General Information: This organism was originally isolated from ticks in a field study on tick-transmitted diseases of small mammals in Canada. Member of the typhus group of Rickettsiales. Members of this genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, are obligate intracellular pathogens. In both groups, the bacteria are transmitted via an insect, usually a tick, to a host organism where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Rickettsia canadensis was originally thought to be a member of the typhus group of Rickettsiales, however, it is now thought to represent a distict group with the rickettsia.