Query: NC_005955:947500 Bartonella quintana str. Toulouse, complete genome Lineage: Bartonella quintana; Bartonella; Bartonellaceae; Rhizobiales; Proteobacteria; Bacteria General Information: Bartonella quintana str. Toulouse was isolated from human blood in Toulouse, France in 1993. Causative agent of trench fever. This group of alpha proteobacteria are unique among pathogens in that they cause angiogenic lesions. This organism was first identified as the causative agent of louse-born trench fever during World War I. Up to 800 000 were infected in the trenches because of the louse insect vector that was widespread due to poor sanitation. The disease is now found associated with immunocompromized patients, especially HIV patients and homeless alcoholics.
- Sequence; - BLASTN hit (Low score = Light, High score = Dark) - hypothetical protein; - cds: hover for description
General Information: Bacillus cereus 03BB102 was cultured from the blood of a 39 year old San Antonio, Texas welder who died as a result of a severe pneumonia thought to be caused by this microbe. Unlike B. anthracis, the isolate is hemolytic, motile and resistant to gamma phage. However, it is positive for a DFA-based cell wall test for B. anthracis, and it has all or most of the pXO1 pathogenicity island sequences including the sequences for pag, cya and lef. This organism is a soil-dwelling opportunistic pathogen that causes food poisoning in infected individuals. The rapid onset is characterized by nausea and vomiting while the late onset is characterized by diarrhea and abdominal pain. The emetic disease is caused by a small stable dodecadepsipeptide cerulide whereas the diarrheal disease is caused by a heat labile enterotoxin. Some strains produce a potent cytotoxin that forms a pore in the membrane of eukaryotic cells and causes necrotic enteritis (death of intestinal epithelial cells) while the unique tripartite membrane lytic toxin hemolysin BL contributes to the diarrheal disease and destructive infections of the eye.