Pre_GI: OUP Neighbours

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Query: NC_000907:1568867 Haemophilus influenzae Rd KW20, complete genome

D: 34.7841

Host Lineage: Haemophilus influenzae; Haemophilus; Pasteurellaceae; Pasteurellales; Proteobacteria; Bacteria

General Information: Small, nonmotile, Gram-negative bacterium whose only natural host is human. It lacks an important fimbrial gene cluster that is important for virulence as compared to type b strains and was the first microbe to ever be sequenced. A group of organisms that are either obligate parasites or commensal organisms found in animal mucous membranes. Almost all species require the presence of important growth factors found in the blood of their hosts, including either X factor (protoporphyrin IX or heme) or V factor (nicotinamide adenine dinucleotide (NAD or NADP)). This organism was first isolated in the 1890s during an influenza pandemic by Pfeiffer, and was originally thought to be the source of influenza, although later it was shown to be a secondary pathogen and may be synergistic with the influenza virus. This bacterium is one of the leading causes of meningitis in young children, and it may also cause septicemia, otitis media (inflammation of the middle ear), sinusitis (inflammation of the sinus cavity) and chronic bronchitis. It is highly adapted to its human host and typically lives in the nasopharynx and is a major cause of lower respiratory infections in infants and small children in developing countries (type 1b strain), although vaccine use has resulted in the decline of infections. The encapsulated organism can penetrate the blood and avoid both phagocytosis and complement-mediated lysis. All known strains produce neuraminidase and an IgA protease as well as fimbrial adhesins for attachment.

Number of Neighbours: 9




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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandSubject Host Description Compositional Similarity Proposed Island FlowSubject Island D
NC_013416:1748848*Aggregatibacter actinomycetemcomitans D11S-1, complete genome75.8364 %Subject ←→ Query25.7053
NC_015497:3614817Glaciecola agarilytica 4H-3-7+YE-5 chromosome, complete genome78.8603 %Subject ←→ Query26.8361
NC_009998:62000Shewanella baltica OS195 plasmid pS19501, complete sequence75.0031 %Subject ←→ Query27.7116
NC_013416:939668*Aggregatibacter actinomycetemcomitans D11S-1, complete genome77.356 %Subject ←→ Query28.6661
NC_004347:3028000Shewanella oneidensis MR-1, complete genome75.7721 %Subject ←→ Query29.3045
NC_004460:973738Vibrio vulnificus CMCP6 chromosome II, complete sequence75.4044 %Subject ←→ Query30.5138
NC_015581:1043394Thioalkalimicrobium cyclicum ALM1 chromosome, complete genome76.348 %Subject ←→ Query32.6716
NC_015581:1133775*Thioalkalimicrobium cyclicum ALM1 chromosome, complete genome75.1562 %Subject ←→ Query33.7044
NC_010995:4525119Cellvibrio japonicus Ueda107, complete genome77.3101 %Subject ←→ Query36.7553