n1_4mer:GRV/n1_4mer:RV = (Global Relative Variance of OU patterns) / (Local Relative Variance of OU patterns)
n0_4mer:D = Distance between local and global OU patterns
n0_4mer:PS = Distance between 2 strands of same DNA molecule
Selected loci indicated by large D, increased GRV associated with decreased RV and moderate increase in PS
NC_009806: Kineococcus radiotolerans SRS30216 plasmid pKRAD01, complete
NCBI: NC_009806
Host Lineage: Kineococcus radiotolerans; Kineococcus; Kineosporiaceae; Actinomycetales; Actinobacteria; Bacteria
General Information: This organism is a coccoid bacterium originally isolated from a high-level radioactive waste cell at the Savannah River Site in Aiken, South Carolina, USA, in 2002. Radiation-resistant bacterium. K. radiotolerans exhibits a high degree of resistance to ionizing gamma-radiation. Cells are also highly resistant to dessication. Kineococcus-like 16S rRNA gene sequences have been reported from the Mojave desert and other arid environments where these bacteria seem to be ubiquitous.Because of its high resistance to ionizing radiation and desiccation, K. radiotolerans has potential use in applications involving in situ biodegradation of problematic organic contaminants from highly radioactive environments. Moreover, comparative functional genomic characterization of this species and other known radiotolerant bacteria such as Deinococcus radiodurans and Rubrobacter xylanophilus will shed light onto the strategies these bacteria use for survival in high radiation environments, as well as the evolutionary origins of radioresistance and their highly efficient DNA repair machinery.This organism produces an orange carotenoid-like pigment. Cell growth occurs between 11-41 C, pH 5-9, and in the presence of <5% NaCl and <20% glucose. Carbohydrates and alcohols are primary growth substrates.