Pre_GI Gene

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Host: NC_017515 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_017515:1855114 Neisseria meningitidis M04-240196 chromosome, complete genome

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
185511418565231410serine-type D-Ala-D-Ala carboxypeptidaseQuickGO ontologyBLASTP
185746718584741008transposase IS4 familyQuickGO ontologyBLASTP
18585151859042528hypothetical proteinBLASTP
185905318600601008transposase IS4 familyQuickGO ontologyBLASTP
18602461860578333hypothetical proteinBLASTP
18606011860744144hypothetical proteinBLASTP
186084818621101263auxiliary transport protein membrane fusion protein MFP familyQuickGO ontologyBLASTP
186211218642082097peptidase C39 familyQuickGO ontologyBLASTP
18646021864808207hypothetical proteinBLASTP
186481518659781164cupin family proteinQuickGO ontologyBLASTP
18660401866579540transposase IS4 familyQuickGO ontologyBLASTP
186823618692431008transposase IS4 familyQuickGO ontologyBLASTP
186941518705841170methionine adenosyltransferaseQuickGO ontologyBLASTP
18709661871817852lipid A biosynthesis KDO2-lauroyl-lipid IVA acyltransferaseQuickGO ontologyBLASTP
187186118729251065O-sialoglycoprotein endopeptidaseQuickGO ontologyBLASTP
187304118742281188cytochrome c-type biogenesis protein CcsBQuickGO ontologyBLASTP
187422118762362016ResB family proteinQuickGO ontologyBLASTP
18764501877073624cytochrome c family proteinQuickGO ontologyBLASTP