Pre_GI Gene

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Host: NC_015571 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_015571:440605 Porphyromonas gingivalis TDC60, complete genome

Host Lineage: Porphyromonas gingivalis; Porphyromonas; Porphyromonadaceae; Bacteroidales; Bacteroidetes; Bacteria

General Information: This organism is associated with severe and chronic periodontal (tissues surrounding and supporting the tooth) diseases. Progression of the disease is caused by colonization by this organism in an anaerobic environment in host tissues and severe progression results in loss of the tissues supporting the tooth and eventually loss of the tooth itself. The black pigmentation characteristic of this bacterium comes from iron acquisition that does not use the typical siderophore system of other bacteria but accumulates hemin. Peptides appear to be the predominant carbon and energy source of this organism, perhaps in keeping with its ability to destroy host tissue. Oxygen tolerance systems play a part in establishment of the organism in the oral cavity, including a superoxide dismutase. Pathogenic factors include extracellular adhesins that mediate interactions with other bacteria as well as the extracellular matrix, and a host of degradative enzymes that are responsible for tissue degradation and spread of the organism including the gingipains, which are trypsin-like cysteine proteases.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
4406054419571353magnesium transporterQuickGO ontologyBLASTP
441989442765777dimethyladenosine transferaseQuickGO ontologyBLASTP
4428964439451050hypothetical proteinBLASTP
4439764454301455aminoacyl-histidine dipeptidaseQuickGO ontologyBLASTP
445545446426882malonyl CoA-acyl carrier protein transacylaseQuickGO ontologyBLASTP
4466074479621356membrane-bound lytic murein transglycosylase DQuickGO ontologyBLASTP
447972448679708hypothetical proteinBLASTP
448699449568870putative ParB chromosome partitioning proteinQuickGO ontologyBLASTP
449576450352777putative ParA chromosome partitioning proteinQuickGO ontologyBLASTP
450568451446879carbon-nitrogen family hydrolaseQuickGO ontologyBLASTP
451464452402939putative arginine deiminaseQuickGO ontologyBLASTP
452840453226387preprotein translocase subunit SecGQuickGO ontologyBLASTP
453229453936708hypothetical proteinBLASTP
453949454488540hypothetical proteinBLASTP
4544754557341260sigma-54-dependent transcriptional regulatorQuickGO ontologyBLASTP
4557564570241269hypothetical proteinBLASTP
4570614583651305putative Fe-S oxidoreductaseQuickGO ontologyBLASTP
458362459315954signal recognition particle-docking protein FtsYQuickGO ontologyBLASTP
4593424604781137carboxynorspermidine decarboxylaseQuickGO ontologyBLASTP
4604884622511764aspartyl-tRNA synthetaseQuickGO ontologyBLASTP
462682463674993riboflavin biosynthesis protein RibDQuickGO ontologyBLASTP
463699464580882HemK family modification methylaseQuickGO ontologyBLASTP
464577465065489regulatory protein RecXQuickGO ontologyBLASTP
465049465789741competence protein F-like proteinQuickGO ontologyBLASTP
4659194679342016endopeptidase PepOQuickGO ontologyBLASTP