Pre_GI Gene

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Host: NC_014335 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_014335:1329414 Bacillus cereus biovar anthracis str. CI chromosome, complete

Host Lineage: Bacillus cereus; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This strain probably caused lethal anthrax in chimpanzee Leo in the rainforest of the Tai National Park, Cote d'Ivoire. It belongs to a collection of genetically closely related bacteria, isolated in 2001 and 2002 from deceased wild chimpanzees living in this rain forest area. An autopsy showed symptoms typical of anthrax, but the bacterium isolated was motile, unlike B.anthracis. This organism is a soil-dwelling opportunistic pathogen that causes food poisoning in infected individuals. The rapid onset is characterized by nausea and vomiting while the late onset is characterized by diarrhea and abdominal pain. The emetic disease is caused by a small stable dodecadepsipeptide cerulide whereas the diarrheal disease is caused by a heat labile enterotoxin. Some strains produce a potent cytotoxin that forms a pore in the membrane of eukaryotic cells and causes necrotic enteritis (death of intestinal epithelial cells) while the unique tripartite membrane lytic toxin hemolysin BL contributes to the diarrheal disease and destructive infections of the eye.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
132941413306491236sodiumdicarboxylate symporter family proteinQuickGO ontologyBLASTP
133185113331941344potassiumsodium uptake proteinQuickGO ontologyBLASTP
13332281333647420hypothetical proteinBLASTP
13338251334292468putative YtfJ-like proteinQuickGO ontologyBLASTP
13348431335082240hypothetical proteinBLASTP
13352091335382174hypothetical proteinBLASTP
13358641336760897branched-chain amino acid aminotransferaseQuickGO ontologyBLASTP
133707713387771701acetolactate synthase large subunitQuickGO ontologyBLASTP
13387741339283510acetolactate synthase III small subunitQuickGO ontologyBLASTP
133931013403201011ketol-acid reductoisomeraseQuickGO ontologyBLASTP
1340322134184215212-isopropylmalate synthaseQuickGO ontologyBLASTP
1341920134298410653-isopropylmalate dehydrogenaseQuickGO ontologyBLASTP
134298413443781395isopropylmalate isomerase large subunitQuickGO ontologyBLASTP
13443531344937585isopropylmalate isomerase small subunitQuickGO ontologyBLASTP
134524813465101263histidine-tRNA ligaseQuickGO ontologyBLASTP
13464861347121636ATP phosphoribosyltransferaseQuickGO ontologyBLASTP
134713313484221290histidinol dehydrogenaseQuickGO ontologyBLASTP
13484221349006585imidazoleglycerol-phosphate dehydrataseQuickGO ontologyBLASTP
13490071349636630imidazole glycerol phosphate synthase subunit HisHQuickGO ontologyBLASTP
13496091350328720phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomeraseQuickGO ontologyBLASTP
13503221351080759imidazole glycerol phosphate synthase subunit HisFQuickGO ontologyBLASTP
13510771351382306phosphoribosyl-AMP cyclohydrolaseQuickGO ontologyBLASTP
13513931351716324phosphoribosyl-ATP pyrophosphataseQuickGO ontologyBLASTP
135172813527441017histidinol-phosphataseQuickGO ontologyBLASTP