Pre_GI Gene

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Host: NC_007618 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_007618:724238 Brucella melitensis biovar Abortus 2308 chromosome I, complete

Host Lineage: Brucella abortus; Brucella; Brucellaceae; Rhizobiales; Proteobacteria; Bacteria

General Information: This strain is a standard laboratory strain. It is virulent for humans and cattle. Causes bovine brucellosis. They are highly infectious, and can be spread through contact with infected animal products or through the air, making them a potential bioterrorism agent. Once the organism has entered the body, it can become intracellular, and enter the blood and lymphatic regions, multiplying inside phagocytes before eventually causing bacteremia (spread of bacteria through the blood). Virulence may depend on a type IV secretion system which may promote intracellular growth by secreting important effector molecules. This organism was first noticed on the island of Malta. It is the primary cause of bovine brucellosis, which results in enormous (billions of dollars) economic losses due primarily to reproductive failure and food losses. In man, it causes undulant fever, a long debilitating disease that is treated by protracted administration of antibiotics.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
724238724828591hypothetical proteinBLASTP
725049725660612ExonucleaseQuickGO ontologyBLASTP
725985726503519ATPGTP-binding site motif A P-loopQuickGO ontologyBLASTP
7265277280621536GCN5-related N-acetyltransferaseQuickGO ontologyBLASTP
728037728831795Helix-turn-helix motifQuickGO ontologyBLASTP
728856729275420hypothetical proteinBLASTP
729655730551897hypothetical proteinBLASTP
7305517326652115Integrase catalytic domainQuickGO ontologyBLASTP
7336047354421839hypothetical proteinBLASTP
735480735677198hypothetical proteinBLASTP
7359187372251308Beta and gamma crystallinQuickGO ontologyBLASTP
739186740019834hypothetical proteinBLASTP
740306740917612Bacterial SH3-like regionQuickGO ontologyBLASTP
741077741325249hypothetical proteinBLASTP
741428741583156hypothetical proteinBLASTP
7415707427391170CysMet metabolism pyridoxal-phosphate-dependent enzymeCystathionine beta-lyase bacterialQuickGO ontologyBLASTP
742950743717768PA-phosphatase related phosphoesteraseQuickGO ontologyBLASTP