Pre_GI Gene

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Host: NC_006142 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_006142:243899 Rickettsia typhi str. Wilmington, complete genome

Host Lineage: Rickettsia typhi; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, is composed of obligate intracellular pathogens. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. Transovarial transmission (from mother to offspring) occurs in the invertebrate host. Rickettsia typhi causes murine typhus and is an obligate intracellular pathogen that infects both the flea vector and hosts such as human, rat, and mouse. In the flea vector, the bacterium penetrates the gut epithelial barrier and is found in the feces which become infective.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
243899244480582ribonuclease HIIQuickGO ontologyBLASTP
2445452465331989excinuclease ABC subunit BQuickGO ontologyBLASTP
246610246924315glutaredoxin 3QuickGO ontologyBLASTP
2470192487971779probable ATP binding cassette transporterQuickGO ontologyBLASTP
2500642527812718DNA gyrase subunit AQuickGO ontologyBLASTP
254055254582528peptide deformylaseQuickGO ontologyBLASTP
254594255490897methionyl-tRNA formyltransferaseQuickGO ontologyBLASTP
255711255851141hypothetical proteinBLASTP
256226258987276223S ribosomal RNAQuickGO ontologyBLASTP
258437258853417hypothetical proteinBLASTP
2592132593131015S ribosomal RNAQuickGO ontologyBLASTP
2595032605761074probable ATPaseQuickGO ontologyBLASTP
2612102623371128S-adenosylmethioninetRNA ribosyltransferase-isomeraseQuickGO ontologyBLASTP