Pre_GI Gene

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Host: NC_005126 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_005126:949226 Photorhabdus luminescens subsp. laumondii TTO1, complete genome

Host Lineage: Photorhabdus luminescens; Photorhabdus; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This strain was isolated on Trinidad and Tobago. It is a symbiont of the nematode Heterorhabditis bacteriophora. Bioluminescent bacterium. This organism is unusual in that it is symbiotic within one insect, and pathogenic in another, the only organism that is known to exhibit this dual phenotype. Enzymes are then released by the bacteria that result in rapid degradation of the insect body, allowing both bacteria and nematode to feed and reproduce. During this period Photorhabdus luminescens releases bacteriocidal products, including antibiotics and bacteriocins, that prevent infection of the larva by competitive microbes. The result is promotion of Photorhabdus luminescens-nematode interactions that result in continuation of the symbiotic relationship. In order to engage in a symbiotic relationship with the nematode and a pathogenic one with the insect larva, the bacterium encodes specific factors that encourage both. These include a large number of genes that code for secreted toxins and enzymes, as well as genes that encode products for the production of antibiotics and bacteriocins. Secretion of these products occurs by an array of systems including type I, type II, and type III secretion systems. The type III system is closely related to the Yersinia plasmid-encoded type III system. Genes that promote symbiotic relationships are also encoded on genomic islands on the chromosome including some that affect nematode development. Virulence genes appear to be active during exponential growth. Symbiotic genes appear to function during stationary phase (post-exponential) growth. The switch from one state to another is controlled. Photorhabdus luminescens is capable of giving off light, a complex process that requires the products of the lux operon.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
9504089515651158hypothetical proteinBLASTP
9538409550661227hypothetical proteinBLASTP
9554189565751158hypothetical proteinBLASTP
9565809579381359hypothetical proteinBLASTP
9579419600822142hypothetical proteinBLASTP
960454960750297hypothetical protein
960810960950141hypothetical protein
9628659640341170beta-lactamase class C cephalosporinaseQuickGO ontologyBLASTP
9665239677461224Putative tagatose-6-phosphate ketosealdose isomeraseQuickGO ontologyBLASTP
967712968194483PTS system N-acetylgalactosamine-specific IIB component 2 EIIB-AGA N-acetylgalactosamine-permease IIB component 2 Phosphotransferase enzyme IIQuickGO ontologyBLASTP
968992969885894PTS system N-acetylgalactosamine-specific IID component EIID-AGA N-acetylgalactosamine-permease IID component Phosphotransferase enzyme II D coQuickGO ontologyBLASTP