Pre_GI Gene

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Host: NC_003155 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_003155:5163382 Streptomyces avermitilis MA-4680, complete genome

Host Lineage: Streptomyces avermitilis; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain (ATCC 31267) was isolated and characterized in 1978 by R. Burg and colleagues from a soil sample collected in Shizuoka Prefecture, Japan. Antibiotic-producing bacterium. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes. This organism is a well known producer of the anti-parasitic agent avermectin which is widely used to rid livestock of worm and insect infestations and to protect large numbers of people from river blindness in sub-Saharan Africa.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
516338251645481167lipid-transfer proteinQuickGO ontologyBLASTP
51645455164940396hypothetical proteinBLASTP
516493751660731137acyl-CoA dehydrogenaseQuickGO ontologyBLASTP
51660755167025951hypothetical proteinBLASTP
516702251683111290acyl-CoA dehydrogenaseQuickGO ontologyBLASTP
51685725168808237hypothetical proteinBLASTP
51691895170106918hypothetical proteinBLASTP
51725335172976444IS1647-like transposaseQuickGO ontologyBLASTP
51728685173350483IS1647-like transposaseQuickGO ontologyBLASTP
51736615174278618hypothetical proteinBLASTP
51743455174863519hypothetical protein
517496551763681404hypothetical proteinBLASTP
51765765176899324hypothetical proteinBLASTP
51769895177345357hypothetical proteinBLASTP
51773425177554213hypothetical protein
5177691517777787tRNA-SerQuickGO ontologyBLASTP
517784151792591419serine proteaseQuickGO ontologyBLASTP
51795445180353810glycerophosphoryl diester phosphodiesteraseQuickGO ontologyBLASTP
51804725181125654regulatory proteinQuickGO ontologyBLASTP
51813315182296966hypothetical proteinBLASTP
51826325183207576hypothetical proteinBLASTP
51832635183928666hypothetical proteinBLASTP
518451651859101395magnesium or manganese-dependent protein phosphataseQuickGO ontologyBLASTP
518599551874581464aminopeptidase PQuickGO ontologyBLASTP