Pre_GI Gene

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Host: NC_000919 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_000919:746875 Treponema pallidum subsp. pallidum str. Nichols, complete genome

Host Lineage: Treponema pallidum; Treponema; Spirochaetaceae; Spirochaetales; Spirochaetes; Bacteria

General Information: This strain was originally isolated in 1912 from a neurosyphilitic patient and is virulent. This organism is the causative agent of endemic and venereal syphilis. This sexual transmitted disease was first discovered in Europe at the end of the fifteenth century, however, the causative agent was not identified until 1905. At one time syphilis was the third most commonly reported communicable disease in the USA. Syphilis is characterized by multiple clinical stages and long periods of latent, asymptomatic infection. Although effective therapies have been available since the introduction of penicillin, syphilis remains a global health problem. This organisms is divided into subspecies each of which causes a specific disease. T. pallidum causes the venereal disease syphilis. T. pertenue, T. carateum and T. endemicum cause the skin infections yaws, pinta and bejel, respectively.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
7468757479691095octaprenyl-diphosphate synthaseQuickGO ontologyBLASTP
7482627494731212methylgalactoside ABC transporter periplasmic galactose-binding protein mglB-2QuickGO ontologyBLASTP
7495937510831491methylgalactoside ABC transporter ATP binding protein mglAQuickGO ontologyBLASTP
7510987526931596methylgalactoside ABC transporter permease protein mglCQuickGO ontologyBLASTP
7528217548812061DNA recombinase recGQuickGO ontologyBLASTP
7549377559501014immunity protein mccFQuickGO ontologyBLASTP
7559517573331383GTP-binding protein EngAQuickGO ontologyBLASTP
757369757950582hypothetical proteinBLASTP
757943758701759hypothetical proteinBLASTP
7587297599521224recA protein recAQuickGO ontologyBLASTP
7602137615351323hypothetical proteinBLASTP
761695762372678510-methenyltetrahydrofolate synthetase putativeQuickGO ontologyBLASTP
7624607642531794phosphoribosylglycinamide formyltransferase putativeQuickGO ontologyBLASTP
764241765077837nicotinamidase putativeQuickGO ontologyBLASTP
765139765747609hypothetical proteinBLASTP
765778766323546hypothetical proteinBLASTP
766320766430111hypothetical proteinBLASTP
766436766828393hypothetical proteinBLASTP