Pre_GI Gene

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Host: NC_005957 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_005957:4502733 Bacillus thuringiensis serovar konkukian str. 97-27, complete

Host Lineage: Bacillus thuringiensis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This organism was isolated from a case of severe human tissue necrosis which is unusual since human infections by this organism are rare. Produces insect toxinT his organism, also known as BT, is famous for the production of an insecticidal toxin. The bacterium was initially discovered as a pathogen of various insects and was first used as an insecticidal agent in the early part of this century. This organism, like many other Bacilli, is found in the soil, where it leads a saprophytic existence, but becomes an opportunistic pathogen of insects when ingested. The specific activity of the toxin towards insects and its lack of toxicity to animals has made this organism a useful biocontrol agent. The delta-endotoxin, which is produced during the sporulation part of the life cycle, causes midgut paralysis and disruption of feeding by the infected insect host. The delta-endotoxin, which is produced during the sporulation part of the life cycle, causes midgut paralysis and disruption of feeding by the infected insect host. The delta-endotoxin, which is produced during the sporulation part of the life cycle, causes midgut paralysis and disruption of feeding by the infected insect host. The presence of a parasporal crystal, which is outside the exosporium of the endospore, is indicative of production of the toxin, and serves as a marker for this species.Activation of the toxin typically requires a high pH environment such as the alkaline environments in insect midguts followed by proteolysis. Various toxin genes specific for a variety of insects have been studied, and many are now being used in genetically modified plants which have been engineered to produce the toxin themselves, eliminating the need to produce sufficient amounts of B. thuringiensis spores.


This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
45027334503056324transcriptional regulator ArsR familyQuickGO ontologyBLASTP
45030574503488432hypothetical proteinBLASTP
45038614504139279hypothetical proteinBLASTP
45041744504356183hypothetical proteinBLASTP
45043584504594237hypothetical proteinBLASTP
45048504505344495transcriptional regulator CarD familyQuickGO ontologyBLASTP
45054174506202786glucose-1-dehydrogenaseQuickGO ontologyBLASTP
45062164507073858glucose uptake proteinQuickGO ontologyBLASTP
45071104507529420hypothetical proteinBLASTP
45076234507856234molybdopterin converting factor subunit 1QuickGO ontologyBLASTP
45078594508323465molybdopterin converting factor large subunit subunit 2QuickGO ontologyBLASTP
45083204508835516molybdopterin-guanine dinucleotide biosynthesis protein BQuickGO ontologyBLASTP
450880545100941290molybdopterin biosynthesis proteinQuickGO ontologyBLASTP
45101784510663486molybdenum cofactor biosynthesis protein CQuickGO ontologyBLASTP
451070245117151014molybdopterin biosynthesis protein MoeBQuickGO ontologyBLASTP
451173245127511020molybdenum cofactor biosynthesis protein AQuickGO ontologyBLASTP
451291945160863168collagen-like proteinQuickGO ontologyBLASTP
45162484516571324hypothetical proteinBLASTP
45165924516816225hypothetical proteinBLASTP
45168944517199306rhodanese-like domain proteinQuickGO ontologyBLASTP
45174004517582183hypothetical proteinBLASTP
451763245187561125homoserine O-acetyltransferaseQuickGO ontologyBLASTP
451890945212302322spore germination proteinQuickGO ontologyBLASTP
452124845223481101spore germination protein IBQuickGO ontologyBLASTP
452231845234031086spore germination proteinQuickGO ontologyBLASTP
45234824523679198hypothetical proteinBLASTP
45238684524290423hypothetical proteinBLASTP
45243354525081747hypervariable Bacillus group-specific proteinQuickGO ontologyBLASTP
452533845277462409leucyl-tRNA synthetaseQuickGO ontologyBLASTP
452821845294111194permease possible multidrug resistance proteinQuickGO ontologyBLASTP