Pre_GI Gene

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Host: NC_004631 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_004631:862002 Salmonella enterica subsp. enterica serovar Typhi Ty2, complete

Host Lineage: Salmonella enterica; Salmonella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This pathogenic strain of Salmonella typhi was isolated in the early 1970s. It contains no multidrug resistance plasmids and has been used for vaccine development. This serovar is a human-specific organism that causes the life-threatening illness Typhoid fever which is acquired by coming into contact with contaminated food or water. Annually, 17 million people are infected, with 600,000 fatalities, mostly in developing countries. It contains multiple fimbrial operons that may be used to create extracellular appendages for attachment and entry into host intestinal epithelial cells. Causes enteric infections. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis, from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.


StartEndLengthCDS descriptionQuickGO ontologyBLASTP
8632778644971221putative glycosyl transferaseQuickGO ontologyBLASTP
8645088659111404hypothetical proteinBLASTP
866089866982894UTP-glucose-1-phosphate uridylyltransferaseQuickGO ontologyBLASTP
8673598684441086dTDP-glucose 46-dehydrataseQuickGO ontologyBLASTP
868444869343900dTDP-4-dehydrorhamnose reductaseQuickGO ontologyBLASTP
869391870269879TDP-glucose pyrophosphorylaseQuickGO ontologyBLASTP
870270870821552dTDP-4-dehydrorhamnose 35-epimeraseQuickGO ontologyBLASTP
870827871801975CDP-6-deoxy-delta-34-glucoseen reductaseQuickGO ontologyBLASTP
871817872590774glucose-1-phosphate cytidylyltransferaseQuickGO ontologyBLASTP
8725958736741080CDP-glucose 46-dehydrataseQuickGO ontologyBLASTP
8737018750141314putative dehydratase RfbHQuickGO ontologyBLASTP
875049875888840paratose synthaseQuickGO ontologyBLASTP
8758858769011017CDP-tyvelose-2-epimeraseQuickGO ontologyBLASTP
8769728782701299putative O-antigen transporterQuickGO ontologyBLASTP
8782728792731002putative glycosyl transferaseQuickGO ontologyBLASTP
8798488809091062putative glycosyl transferaseQuickGO ontologyBLASTP
880910881854945putative rhamnosyltransferaseQuickGO ontologyBLASTP
8818558832941440mannose-1-phosphate guanylyltransferaseQuickGO ontologyBLASTP
8832818847141434phosphomannomutaseQuickGO ontologyBLASTP
8847868862161431undecaprenyl-phosphate galactosephosphotransferaseQuickGO ontologyBLASTP
88638088778614076-phosphogluconate dehydrogenaseQuickGO ontologyBLASTP
8880238891891167UDP-glucose 6-dehydrogenaseQuickGO ontologyBLASTP
889332890315984polysaccharide chain length regulatorQuickGO ontologyBLASTP
890396891007612bifunctional phosphoribosyl-AMP cyclohydrolasephosphoribosyl-ATP pyrophosphatase proteinQuickGO ontologyBLASTP
891001891777777imidazole glycerol phosphate synthase subunit HisFQuickGO ontologyBLASTP
8917598924967381-5-phosphoribosyl-5-5- phosphoribosylaminomethylideneamino imidazole-4-carboxamide isomeraseQuickGO ontologyBLASTP
892496893086591imidazole glycerol phosphate synthase subunit HisHQuickGO ontologyBLASTP
8930868941531068imidazole glycerol-phosphate dehydratasehistidinol phosphataseQuickGO ontologyBLASTP
8941508952291080histidinol-phosphate aminotransferaseQuickGO ontologyBLASTP
8952268965301305histidinol dehydrogenaseQuickGO ontologyBLASTP