Pre_GI Gene

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Host: NC_003888 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_003888:6103534 Streptomyces coelicolor A3(2), complete genome

Host Lineage: Streptomyces coelicolor; Streptomyces; Streptomycetaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Well-studied antiobiotic-producing bacterium. These bacteria are widely distributed in nature, especially in the soil. The characteristic earthy smell of freshly plowed soil is actually attributed to the aromatic terpenoid geosmin produced by species of Streptomyces. There are currently 364 known species of this genus, many of which are the most important industrial producers of antibiotics and other secondary metabolites of antibacterial, antifungal, antiviral, and antitumor nature, as well as immunosuppressants, antihypercholesterolemics, etc. Streptomycetes are crucial in the soil environment because their diverse metabolism allows them to degrade the insoluble remains of other organisms, including recalcitrant compounds such as lignocelluloses and chitin. Streptomycetes produce both substrate and aerial mycelium. The latter shows characteristic modes of branching, and in the course of the streptomycete complex life cycle, these hyphae are partly transformed into chains of spores, which are often called conidia or arthrospores. An important feature in Streptomyces is the presence of type-I peptidoglycan in the cell walls that contains characteristic interpeptide glycine bridges. Another remarkable trait of streptomycetes is that they contain very large (~8 million base pairs which is about twice the size of most bacterial genomes) linear chromosomes with distinct telomeres. These rearrangements consist of the deletion of several hundred kilobases, often associated with the amplification of an adjacent sequence, and lead to metabolic diversity within the Streptomyces group. Sequencing of several strains of Streptomyces is aimed partly on understanding the mechanisms involved in these diversification processes. This bacterium is a soil-dwelling filamentous organism responsible for producing more than half of the known natural antibiotics. It is a well-studied species of Streptomyces and genetically is the best known representative.


This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
61035346104052519hypothetical proteinBLASTP
61041096104417309hypothetical proteinBLASTP
61044766104868393hypothetical proteinBLASTP
610486861064931626hypothetical proteinBLASTP
610649061076381149hypothetical proteinBLASTP
61078176108128312hypothetical proteinBLASTP
61081256108415291hypothetical protein
61084666108660195transcriptional regulatorQuickGO ontologyBLASTP
61087556109456702hypothetical proteinBLASTP
61095156109712198hypothetical protein
61100516110413363hypothetical protein
61111776111392216transcriptional regulatorQuickGO ontologyBLASTP
611155461138242271ATP binding proteinQuickGO ontologyBLASTP
61141086114659552hypothetical protein
61151246115315192transcriptional regulatorQuickGO ontology
61153126115662351hypothetical protein
61157306116218489hypothetical proteinBLASTP
61162056116621417hypothetical proteinBLASTP
61170396117482444hypothetical proteinBLASTP
61177946118300507hypothetical proteinBLASTP
611837061207602391recombinaseQuickGO ontologyBLASTP
61210436121885843sigma factor WhiGQuickGO ontologyBLASTP
61220146122571558transcriptional regulatorQuickGO ontologyBLASTP
61225256123205681hypothetical proteinBLASTP
6123494612442693330S ribosomal protein S2QuickGO ontologyBLASTP
61245216125357837elongation factor TsQuickGO ontologyBLASTP
61255636126324762uridylate kinaseQuickGO ontologyBLASTP
61265036127060558ribosome recycling factorQuickGO ontologyBLASTP
612706061282351176integral membrane proteinQuickGO ontologyBLASTP
612836061310202661ATP GTP-binding proteinQuickGO ontologyBLASTP
61324376132679243hypothetical protein
613349161357972307traSAintegrase fusion proteinQuickGO ontologyBLASTP
61362896137068780transcriptional regulatorQuickGO ontologyBLASTP
61371566137551396mutT-like proteinQuickGO ontologyBLASTP
61378816138768888integral membrane proteinQuickGO ontologyBLASTP
61387656139295531hypothetical proteinBLASTP
61394026139869468hypothetical protein
61398876140843957transposaseQuickGO ontologyBLASTP
61408196141583765hypothetical proteinBLASTP
61416506142177528hypothetical protein
61422616142887627hypothetical protein
614301961441251107hypothetical proteinBLASTP
614434961454701122solute binding lipoproteinQuickGO ontologyBLASTP
614546761471281662ABC transporter integral membrane proteinQuickGO ontologyBLASTP
614713161481771047ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
61482026149002801hypothetical proteinBLASTP
61490646149768705hypothetical protein
614992561511091185hypothetical proteinBLASTP
61511366151543408hypothetical proteinBLASTP
615164961531091461integral membrane proteinQuickGO ontology
61530916153867777ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
615407361554461374hypothetical proteinBLASTP