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Query: NC_017265:3821890 Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,

Start: 3821890, End: 3845387, Length: 23498

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis consists of three biotypes or serovars, Antiqua, Mediavalis, and Orientalis, that are associated with three major pandemics throughout human history. pMT1 encodes a protein, murine toxin, that aids rat-to-human transmission by enhancing survival of the organism in the flea midgut. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.

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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_013716:5201097*5201097527659975503Citrobacter rodentium ICC168, complete genome7e-1073.8BLASTN svgBLASTP svg
NC_015663:18690001869000191219543196Enterobacter aerogenes KCTC 2190 chromosome, complete genome2e-1385.7BLASTN svgBLASTP svg
NC_009778:17174581717458175914341686Enterobacter sakazakii ATCC BAA-894, complete genome1e-73285BLASTN svgBLASTP svg
NC_014306:19819561981956200836926414Erwinia billingiae Eb661, complete genome8e-1383.8BLASTN svgBLASTP svg
NC_014306:24763162476316249830421989Erwinia billingiae Eb661, complete genome4e-0867.9BLASTN svgBLASTP svg
NC_004547:442927*44292748635443428Erwinia carotovora subsp. atroseptica SCRI1043, complete genome2e-0765.9BLASTN svgBLASTP svg
NC_012962:25877562587756263945151696Photorhabdus asymbiotica, complete genome1e-1489.7BLASTN svgBLASTP svg
NC_012962:48489948489951520630308Photorhabdus asymbiotica, complete genome5e-1487.7BLASTN svgBLASTP svg
NC_012962:3864000*3864000389221428215Photorhabdus asymbiotica, complete genome3e-21111BLASTN svgBLASTP svg
NC_012962:34999003499900355871558816Photorhabdus asymbiotica, complete genome2e-19105BLASTN svgBLASTP svg
NC_012962:16616831661683171390552223Photorhabdus asymbiotica, complete genome2e-19105BLASTN svgBLASTP svg
NC_005126:58900058900061853029531Photorhabdus luminescens subsp. laumondii TTO1, complete genome3e-0661.9BLASTN svgBLASTP svg
NC_005126:43337674333767439509961333Photorhabdus luminescens subsp. laumondii TTO1, complete genome4e-0867.9BLASTN svgBLASTP svg
NC_005126:16138181613818165143837621Photorhabdus luminescens subsp. laumondii TTO1, complete genome4e-0867.9BLASTN svgBLASTP svg
NC_005126:13154741315474135150136028Photorhabdus luminescens subsp. laumondii TTO1, complete genome4e-0867.9BLASTN svgBLASTP svg
NC_003296:13413531341353136699725645Ralstonia solanacearum GMI1000 plasmid pGMI1000MP, complete4e-0867.9BLASTN svgBLASTP svg
NC_015566:46621714662171468741325243Serratia sp. AS12 chromosome, complete genome5e-20107BLASTN svgBLASTP svg
NC_010159:11012411101241112572024480Yersinia pestis Angola, complete genome045810BLASTN svgBLASTP svg
NC_010159:17940001794000181359119592Yersinia pestis Angola, complete genome2e-167597BLASTN svgBLASTP svg
NC_008150:22071982207198223127724080Yersinia pestis Antiqua, complete genome9e-170605BLASTN svgBLASTP svg
NC_008150:35294303529430355292623497Yersinia pestis Antiqua, complete genome046100BLASTN svgBLASTP svg
NC_005810:32383913238391326081922429Yersinia pestis biovar Microtus str. 91001, complete genome036210BLASTN svgBLASTP svg
NC_005810:25496802549680258809938420Yersinia pestis biovar Microtus str. 91001, complete genome2e-167597BLASTN svgBLASTP svg
NC_003143:27784942778494279956221069Yersinia pestis CO92, complete genome9e-170605BLASTN svgBLASTP svg
NC_003143:64555964555966798722429Yersinia pestis CO92, complete genome036250BLASTN svgBLASTP svg
NC_004088:1851500*1851500188954638047Yersinia pestis KIM, complete genome4e-172613BLASTN svgBLASTP svg
NC_004088:39559333955933398002524093Yersinia pestis KIM, complete genome046120BLASTN svgBLASTP svg
NC_008149:23373362337336236141524080Yersinia pestis Nepal516, complete genome9e-170605BLASTN svgBLASTP svg
NC_006155:41055424105542412736821827Yersinia pseudotuberculosis IP 32953, complete genome030840BLASTN svgBLASTP svg
NC_006155:29795002979500301649636997Yersinia pseudotuberculosis IP 32953, complete genome0795BLASTN svgBLASTP svg
NC_010634:40457944045794406762021827Yersinia pseudotuberculosis PB1/+, complete genome030810BLASTN svgBLASTP svg
NC_010634:28946312894631293584741217Yersinia pseudotuberculosis PB1/+, complete genome0787BLASTN svgBLASTP svg
NC_010465:17907391790739181268021942Yersinia pseudotuberculosis YPIII, complete genome0795BLASTN svgBLASTP svg