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Query: NC_017063:775337 Helicobacter pylori ELS37 chromosome, complete genome

Start: 775337, End: 798127, Length: 22791

Host Lineage: Helicobacter pylori; Helicobacter; Helicobacteraceae; Campylobacterales; Proteobacteria; Bacteria

General Information: This genus consists of organisms that colonize the mucosal layer of the gastrointestinal tract or are found enterohepatically (in the liver). It was only recently discovered (1983) by two Australians (Warren and Marshall) that this organism was associated with peptic ulcers. It is one of the most common chronic infectious organisms, and is found in half the world's population. This organism attacks the gastric epithilial surface, resulting in chronic gastritis, and can cause more severe diseases including those that lead to gastric carcinomas and lymphomas, peptic ulcers, and severe diarrhea. It is an extracellular pathogen that persists in the gastric environment, which has a very low pH, by production of the urease enzyme, which converts urea to ammonia and carbon dioxide, a process which can counteract the acidic environment by production of a base. The toxins include cytolethal distending toxin, vacuolating cytotoxin (VacA) that induces host epithelial cell apopoptosis (cell death), and the cytotoxin associated antigen (CagA) which results in alteration to the host cell signalling pathways. The CagA protein is translocated into host cells by a type IV secretion system encoded by the cag pathogenicity island.

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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_009850:972692*97269299808925398Arcobacter butzleri RM4018, complete genome5e-1177.8BLASTN svgBLASTP svg
NC_007530:5033095*5033095507221139117Bacillus anthracis str. 'Ames Ancestor', complete genome3e-0661.9BLASTN svgBLASTP svg
NC_003997:5032969*5032969507209939131Bacillus anthracis str. Ames, complete genome3e-0661.9BLASTN svgBLASTP svg
NC_005945:5053000*5053000507465121652Bacillus anthracis str. Sterne, complete genome3e-0661.9BLASTN svgBLASTP svg
NC_012472:5094009*5094009511312419116Bacillus cereus 03BB102, complete genome3e-0661.9BLASTN svgBLASTP svg
NC_014335:5005267*5005267502562020354Bacillus cereus biovar anthracis str. CI chromosome, complete3e-0661.9BLASTN svgBLASTP svg
NC_005957:5037499*5037499507811440616Bacillus thuringiensis serovar konkukian str. 97-27, complete3e-0661.9BLASTN svgBLASTP svg
NC_008600:5046000*5046000510070354704Bacillus thuringiensis str. Al Hakam, complete genome3e-0661.9BLASTN svgBLASTP svg
NC_012039:412837*41283745648543649Campylobacter lari RM2100, complete genome1e-0869.9BLASTN svgBLASTP svg
NC_005061:647567*64756767214524579Candidatus Blochmannia floridanus, complete genome2e-1075.8BLASTN svgBLASTP svg
NC_010698:81991281991284430024389Helicobacter pylori Shi470, complete genome0878BLASTN svgBLASTP svg
NC_013730:1572889*1572889159761124723Spirosoma linguale DSM 74, complete genome2e-1075.8BLASTN svgBLASTP svg