Pre_GI: BLASTP Hits

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Query: NC_017063:775337:780539 Helicobacter pylori ELS37 chromosome, complete genome

Start: 780539, End: 781306, Length: 768

Host Lineage: Helicobacter pylori; Helicobacter; Helicobacteraceae; Campylobacterales; Proteobacteria; Bacteria

General Information: This genus consists of organisms that colonize the mucosal layer of the gastrointestinal tract or are found enterohepatically (in the liver). It was only recently discovered (1983) by two Australians (Warren and Marshall) that this organism was associated with peptic ulcers. It is one of the most common chronic infectious organisms, and is found in half the world's population. This organism attacks the gastric epithilial surface, resulting in chronic gastritis, and can cause more severe diseases including those that lead to gastric carcinomas and lymphomas, peptic ulcers, and severe diarrhea. It is an extracellular pathogen that persists in the gastric environment, which has a very low pH, by production of the urease enzyme, which converts urea to ammonia and carbon dioxide, a process which can counteract the acidic environment by production of a base. The toxins include cytolethal distending toxin, vacuolating cytotoxin (VacA) that induces host epithelial cell apopoptosis (cell death), and the cytotoxin associated antigen (CagA) which results in alteration to the host cell signalling pathways. The CagA protein is translocated into host cells by a type IV secretion system encoded by the cag pathogenicity island.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_013740:15401:359193591936713795Acidaminococcus fermentans DSM 20731, complete genomeglutamate racemase2e-1066.2
NC_013851:759500:771805771805772653849Allochromatium vinosum DSM 180 chromosome, complete genomeglutamate racemase2e-0962.8
NC_012659:4273606:429097242909724291781810Bacillus anthracis str. A0248, complete genomeglutamate racemase2e-23109
NC_003997:4273579:429094542909454291754810Bacillus anthracis str. Ames, complete genomeglutamate racemase2e-23109
NC_006270:2850354:286942128694212870236816Bacillus licheniformis ATCC 14580, complete genomeglutamate racemase8e-27120
NC_006322:2851215:286963428696342870452819Bacillus licheniformis ATCC 14580, complete genomeRacE7e-27120
NC_013791:579842:597334597334598143810Bacillus pseudofirmus OF4 chromosome, complete genomeglutamate racemase2e-24112
NC_019896:1483073:148786214878621488662801Bacillus subtilis subsp. subtilis str. BSP1 chromosome, completeGlutamate racemase 21e-1687
NC_017195:2498113:253666625366662537259594Bacillus subtilis subsp. subtilis str. RO-NN-1 chromosome, completeglutamate racemase2e-0653.1
NC_014171:4317520:435183043518304352639810Bacillus thuringiensis BMB171 chromosome, complete genomeglutamate racemase2e-23109
NC_008390:2448379:246933624693362470199864Burkholderia cepacia AMMD chromosome 1, complete sequenceglutamate racemase5e-0755.1
NC_014392:1935130:194685719468571947660804Caldicellulosiruptor obsidiansis OB47 chromosome, complete genomeglutamate racemase1e-22106
NC_008599:596849:600434600434601195762Campylobacter fetus subsp. fetus 82-40, complete genomeglutamate racemase1e-1170.1
NC_012039:53497:666316663167371741Campylobacter lari RM2100, complete genomeglutamate racemase2e-55216
NC_014909:662500:679702679702680547846Candidatus Blochmannia vafer str. BVAF chromosome, complete genomeglutamate racemase6e-1064.7
NC_010424:1563033:159117515911751591996822Candidatus Desulforudis audaxviator MP104C, complete genomeglutamate racemase2e-1583.2
NC_018664:159291:161074161074161889816Clostridium acidurici 9a chromosome, complete genomeglutamate racemase MurI5e-2098.2
NC_014393:4646000:466042546604254661204780Clostridium cellulovorans 743B chromosome, complete genomeglutamate racemase2e-1273.2
NC_014376:597000:597062597062597880819Clostridium saccharolyticum WM1 chromosome, complete genomeglutamate racemase1e-22107
NC_015856:3912195:391444439144443915316873Collimonas fungivorans Ter331 chromosome, complete genomeglutamate racemase6e-1167.8
NC_015389:1610756:163012616301261631055930Coriobacterium glomerans PW2 chromosome, complete genomeglutamate racemase4e-1788.2
NC_010545:1691999:171368817136881714554867Corynebacterium urealyticum DSM 7109, complete genomehypothetical protein2e-1789.7
NC_015161:2060369:2080000208000020810971098Deinococcus proteolyticus MRP chromosome, complete genomeGlutamate racemase3e-1375.9
NC_018515:4442500:445272544527254453621897Desulfosporosinus meridiei DSM 13257 chromosome, complete genomeglutamate racemase2e-1789.4
NC_016803:2431672:243302724330272433866840Desulfovibrio desulfuricans ND132 chromosome, complete genomeglutamate racemase4e-23108
NC_011297:1167615:118510611851061185906801Dictyoglomus thermophilum H-6-12, complete genomeglutamate racemase3e-0962.4
NC_010468:4455201:446578944657894466577789Escherichia coli ATCC 8739, complete genomeglutamate racemase2e-0653.1
CU928160:4248621:425465942546594255516858Escherichia coli IAI1 chromosome, complete genomeglutamate racemase3e-0652.4
NC_000913:4159090:416345141634514164308858Escherichia coli K12, complete genomeglutamate racemase3e-0652.4
NC_010473:4256000:426314842631484264005858Escherichia coli str. K-12 substr. DH10B, complete genomeglutamate racemase3e-0652.4
NC_010376:606000:609188609188609973786Finegoldia magna ATCC 29328, complete genomeglutamate racemase2e-1892.8
NC_009613:2353185:236321923632192363998780Flavobacterium psychrophilum JIP02/86, complete genomeglutamate racemase1e-1273.6
NC_014666:7152782:7154964715496471559951032Frankia sp. EuI1c chromosome, complete genomeglutamate racemase1e-1894
NC_008309:1628939:164593516459351646738804Haemophilus somnus 129PT, complete genomeglutamate racemase2e-1066.2
NC_014256:683384:721382721382722149768Helicobacter pylori B8 chromosome, complete genomeglutamate racemase8e-128456
NC_014633:583858:600692600692601477786Ilyobacter polytropus DSM 2926 plasmid pILYOP01, complete sequenceglutamate racemase4e-1272
NC_009659:997779:998489998489999343855Janthinobacterium sp. Marseille chromosome, complete genomeglutamate racemase3e-1168.9
NC_013166:194614:196632196632197450819Kangiella koreensis DSM 16069, complete genomeglutamate racemase3e-1065.5
NC_009648:4656187:466218346621834662965783Klebsiella pneumoniae subsp. pneumoniae MGH 78578, complete genomeglutamate racemase2e-0756.2
NC_010524:2761394:276914927691492769967819Leptothrix cholodnii SP-6, complete genomeglutamate racemase1e-1170.5
NC_008555:1204000:120467812046781205478801Listeria welshimeri serovar 6b str. SLCC5334, complete genomeglutamate racemase2e-24112
NC_014363:427393:450556450556451329774Olsenella uli DSM 7084 chromosome, complete genomeglutamate racemase2e-0962.8
NC_013406:5020690:503404850340485034824777Paenibacillus sp. Y412MC10 chromosome, complete genomeglutamate racemase8e-1477.8
NC_016641:373623:394657394657395442786Paenibacillus terrae HPL-003 chromosome, complete genomeglutamate racemase7e-1477.8
NC_015177:2271499:228643022864302287242813Pedobacter saltans DSM 12145 chromosome, complete genomeglutamate racemase1e-22107
NC_014039:1766049:178250317825031783357855Propionibacterium acnes SK137 chromosome, complete genomeglutamate racemase1e-21103
NC_016516:1751336:177136317713631772217855Propionibacterium acnes TypeIA2 P.acn33 chromosome, completeglutamate racemase1e-20100
NC_012660:819381:841697841697842491795Pseudomonas fluorescens SBW25 chromosome, complete genomeglutamate racemase1e-0860.1
NC_015410:1202370:122743312274331228248816Pseudomonas mendocina NK-01 chromosome, complete genomeglutamate racemase2e-0756.2
NC_020209:47504:117941117941118735795Pseudomonas poae RE*1-1-14, complete genomeglutamate racemase1e-0963.5
NC_009434:3413461:342588634258863426680795Pseudomonas stutzeri A1501, complete genomeglutamate racemase3e-1065.9
NC_006511:4119332:412364941236494124500852Salmonella enterica subsp. enterica serovar Paratyphi A str. ATCCglutamate racemase2e-0859.3
NC_003198:3586000:360045136004513601233783Salmonella enterica subsp. enterica serovar Typhi str. CT18,glutamate racemase2e-0859.7
NC_017328:2586171:259711025971102597931822Shigella flexneri 2002017 chromosome, complete genomeglutamate racemase5e-1065.1
NC_004337:2548288:255947225594722560293822Shigella flexneri 2a str. 301, complete genomesimilar to glutamate racemase5e-1065.1
NC_008258:2542863:255407825540782554770693Shigella flexneri 5 str. 8401, complete genomehypothetical protein1e-0653.9
NC_013959:83992:102149102149102955807Sideroxydans lithotrophicus ES-1 chromosome, complete genomeglutamate racemase1e-1067
NC_018870:427357:427357427357428238882Thermacetogenium phaeum DSM 12270 chromosome, complete genomeglutamate racemase MurI4e-23108
NC_011184:2723000:274010627401062740891786Vibrio fischeri MJ11 chromosome I, complete sequenceglutamate racemase3e-0858.9
NC_005810:3493607:349981934998193500682864Yersinia pestis biovar Microtus str. 91001, complete genomeglutamate racemase9e-1063.9