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Query: NC_016838:85487:100260 Klebsiella pneumoniae subsp. pneumoniae HS11286 plasmid pKPHS1,

Start: 100260, End: 100550, Length: 291

Host Lineage: Klebsiella pneumoniae; Klebsiella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This organism is the most medically important organism within the genus Klebsiella. It is an environmental organism found in water, soil, and on the surface of plants. Several strains have been isolated from plant tissues and are nitrogen-fixing endophytes that may be a source of nitrogen for the plant. Other strains can become opportunistic pathogens which infect humans, and typically causes hospital-acquired infections in immunocompromised patients. Major sites of infection include the lungs, where it causes a type of pneumonia, and urinary tract infections. Klebsiella can also enter the bloodstream (bacterimia) and cause sepsis. The pathogen can also infect animals and cause inflammation of the uterus in horses as well as more generalized infections in other mammals. This organism expresses numerous pathogenicity factors, including multiple adhesins, capsular polysaccharide, siderophores, and lipopolysaccharide for the evasion of host defenses. The multiple antibiotic resistance genes carried on the chromosome inhibit efforts to clear the organism from infected patients via antibiotic use.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_011601:4856717:4862628486262848657443117Escherichia coli O127:H6 str. E2348/69 chromosome, complete genometype I restriction-modification enzyme R subunit1e-47188
NC_016514:506611:5193375193375224563120Enterobacter cloacae EcWSU1 chromosome, complete genometype I restriction enzyme R protein3e-47186
NC_015761:299386:3128843128843159913108Salmonella bongori NCTC 12419, complete genometype I restriction enzyme9e-44175
NC_012491:743883:7553787553787584763099Brevibacillus brevis NBRC 100599, complete genometype I restriction modification system endonuclease3e-39160
NC_010645:558974:5646425646425677433102Bordetella avium 197N, complete genometype I restriction enzyme EcoR124II R protein2e-37154
NC_005823:1105524:1118133111813311212313099Leptospira interrogans serovar Copenhageni str. Fiocruz L1-130type I restriction enzyme9e-36148
NC_004342:3164500:317983231798323180767936Leptospira interrogans serovar Lai str. 56601 chromosome I,Restriction enzyme type I helicase subunits and related helicases2e-35147
NC_017033:678321:6880396880396911403102Frateuria aurantia DSM 6220 chromosome, complete genomeHsdR family type I site-specific deoxyribonuclease1e-34144
NC_015144:47783:8051080510836113102Weeksella virosa DSM 16922 chromosome, complete genometype I site-specific deoxyribonuclease, HsdR family2e-34144
NC_010278:315941:3274473274473305843138Actinobacillus pleuropneumoniae serovar 3 str. JL03 chromosome,type I site-specific deoxyribonuclease3e-34143
NC_009053:313779:3226483226483257853138Actinobacillus pleuropneumoniae L20, complete genomeputative type I site-specific restriction-modification system, R (restriction) subunit5e-34142
NC_010939:321492:3322653322653353993135Actinobacillus pleuropneumoniae serovar 7 str. AP76, completeputative type I site-specific restriction- modification system, R (restriction) subunit6e-34142
NC_007778:3470661:3480367348036734834833117Rhodopseudomonas palustris HaA2, complete genometype I site-specific deoxyribonuclease, HsdR family5e-33139
NC_014655:1396672:1400184140018414032823099Leadbetterella byssophila DSM 17132 chromosome, complete genometype i site-specific deoxyribonuclease, hsdr family6e-32135
NC_017516:1439775:1442427144242714451922766Neisseria meningitidis H44/76 chromosome, complete genome3e-30130
NC_003112:844000:8588708588708616352766Neisseria meningitidis MC58, complete genomeputative type I restriction enzyme EcoR124II R protein3e-30130
NC_017515:1429317:1434025143402514371233099Neisseria meningitidis M04-240196 chromosome, complete genomeHsdR family type I site-specific deoxyribonuclease3e-30130
NC_014752:1530000:1533219153321915363173099Neisseria lactamica ST-640, complete genome5e-30129
NC_017505:841496:8555268555268586573132Neisseria meningitidis alpha710 chromosome, complete genomeputative type I restriction enzyme EcoR124II R protein1e-29128
NC_017514:1396000:1399124139912414022553132Neisseria meningitidis M01-240149 chromosome, complete genomeHsdR family type I site-specific deoxyribonuclease1e-29128
NC_015761:4355335:436390443639044364362459Salmonella bongori NCTC 12419, complete genome2e-0961.6
NC_008786:2729635:2740582274058227436323051Verminephrobacter eiseniae EF01-2, complete genometype I site-specific deoxyribonuclease, HsdR family8e-0752.4
NC_018607:1505908:151514815151481515738591Brachyspira pilosicoli B2904 chromosome, complete genometype-I restriction endonuclease R subunit HsdR1e-0652
NC_014330:169862:1847931847931878673075Brachyspira pilosicoli 95/1000 chromosome, complete genometype-I restriction endonuclease R subunit HsdR2e-0651.6
NC_018604:1292889:1292889129288912959963108Brachyspira pilosicoli WesB complete genometype-I restriction endonuclease R subunit HsdR2e-0651.6