Pre_GI: BLASTP Hits

Some Help

Query: NC_016822:3923908:3933072 Shigella sonnei 53G, complete genome

Start: 3933072, End: 3934124, Length: 1053

Host Lineage: Shigella sonnei; Shigella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This genus is named for the Japanese scientist (Shiga) who first discovered these organisms in the 1890s. They are closely related to the Escherichia group, and may be considered the same species. These organisms are human-specific pathogens that are transmitted via contaminated food and water and are the leading causes of endemic bacillary dysentery, causing over 160 million cases of infection and 1 million deaths yearly worldwide. The bacteria infect the epithelial lining of the colon, causing acute inflammation by entering the host cell cytoplasm and spreading intercellularly. are extremely virulent organisms that can cause an active infection after a very low exposure. Both the type III secretion system, which delivers effector molecules into the host cell, and some of the translocated effectors such as the invasion plasmid antigens (Ipas), are encoded on the plasmid. The bacterium produces a surface protein that localizes to one pole of the cell (IcsA) which binds to and promotes actin polymerization, resulting in movement of the bacterium through the cell cytoplasm, and eventually to neighboring cells, which results in inflammatory destruction of the mucosal lining. This organism is the leading cause of dysentery in industrialized countries. The disease is usually less severe than other types of Shigella, causing mild diarrhea and dehydration.




Search Results with any or all of these Fields

Host Accession, e.g. NC_0123..Host Description, e.g. Clostri...
Host Lineage, e.g. archae, Proteo, Firmi...
Host Information, e.g. soil, Thermo, Russia



SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_013941:4249871:4257815425781542589661152Escherichia coli O55:H7 str. CB9615 chromosome, complete genomehypothetical protein0662
AC_000091:3995233:4004522400452240055741053Escherichia coli W3110 DNA, complete genomeconserved inner membrane protein0661
NC_010473:3722571:3730609373060937316611053Escherichia coli str. K-12 substr. DH10B, complete genomeconserved inner membrane protein0661
CU928145:3958572:3966629396662939676811053Escherichia coli 55989 chromosome, complete genomeconserved hypothetical protein; putative inner membrane protein0661
CP002185:3822470:3830492383049238315441053Escherichia coli W, complete genomeconserved inner membrane protein0661
NC_000913:3624826:3632864363286436339161053Escherichia coli K12, complete genomeconserved inner membrane protein0661
NC_011748:3958572:3966629396662939676811053Escherichia coli 55989, complete genomeconserved hypothetical protein; putative inner membrane protein0661
NC_012947:248000:2745942745942756461053Escherichia coli 'BL21-Gold(DE3)pLysS AG' chromosome, completehypothetical protein0661
NC_012967:3549880:3565530356553035665821053Escherichia coli B str. REL606 chromosome, complete genomeinner membrane protein0661
NC_011751:4074586:4082607408260740836591053Escherichia coli UMN026 chromosome, complete genomehypothetical protein0655
NC_010498:3838419:3846440384644038474921053Escherichia coli SMS-3-5, complete genomehypothetical protein0654
NC_007613:3470314:3479800347980034808521053Shigella boydii Sb227, complete genomehypothetical protein0649
NC_007384:3897000:390626939062693907243975Shigella sonnei Ss046, complete genomehypothetical protein4e-174610
NC_004741:4160500:417350541735054174421917Shigella flexneri 2a str. 2457T, complete genome1e-76286
NC_008258:3550500:355995735599573560445489Shigella flexneri 5 str. 8401, complete genomehypothetical protein1e-76286