Pre_GI: BLASTP Hits

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Query: NC_016822:1339058:1361440 Shigella sonnei 53G, complete genome

Start: 1361440, End: 1362099, Length: 660

Host Lineage: Shigella sonnei; Shigella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This genus is named for the Japanese scientist (Shiga) who first discovered these organisms in the 1890s. They are closely related to the Escherichia group, and may be considered the same species. These organisms are human-specific pathogens that are transmitted via contaminated food and water and are the leading causes of endemic bacillary dysentery, causing over 160 million cases of infection and 1 million deaths yearly worldwide. The bacteria infect the epithelial lining of the colon, causing acute inflammation by entering the host cell cytoplasm and spreading intercellularly. are extremely virulent organisms that can cause an active infection after a very low exposure. Both the type III secretion system, which delivers effector molecules into the host cell, and some of the translocated effectors such as the invasion plasmid antigens (Ipas), are encoded on the plasmid. The bacterium produces a surface protein that localizes to one pole of the cell (IcsA) which binds to and promotes actin polymerization, resulting in movement of the bacterium through the cell cytoplasm, and eventually to neighboring cells, which results in inflammatory destruction of the mucosal lining. This organism is the leading cause of dysentery in industrialized countries. The disease is usually less severe than other types of Shigella, causing mild diarrhea and dehydration.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_007384:1355060:137859213785921379251660Shigella sonnei Ss046, complete genomehypothetical protein8e-85313
NC_008258:1873805:189354118935411894200660Shigella flexneri 5 str. 8401, complete genomehypothetical protein3e-83307
NC_003197:1945858:197406919740691974728660Salmonella typhimurium LT2, complete genomeputative inner membrane protein2e-76285
NC_011080:1944226:197969319796931980352660Salmonella enterica subsp. enterica serovar Newport str. SL254,inner membrane protein YebE2e-76285
NC_016810:1903426:193163719316371932296660Salmonella enterica subsp. enterica serovar Typhimurium strhypothetical protein2e-76285
NC_016856:1957263:198547419854741986133660Salmonella enterica subsp. enterica serovar Typhimurium str. 14028Sputative inner membrane protein2e-76285
NC_016857:1903426:193163719316371932296660Salmonella enterica subsp. enterica serovar Typhimurium str. ST4/74putative inner membrane protein2e-76285
NC_016860:1943203:196961019696101970269660Salmonella enterica subsp. enterica serovar Typhimurium strhypothetical protein2e-76285
NC_016863:1905454:193366519336651934324660Salmonella enterica subsp. enterica serovar Typhimurium str. UK-1putative inner membrane protein2e-76285
NC_015224:2095816:211006021100602110716657Yersinia enterocolitica subsp. palearctica 105.5R(r) chromosome,putative inner membrane protein5e-63240
NC_013850:1887556:188755618875561888218663Klebsiella variicola At-22 chromosome, complete genomeprotein of unknown function DUF5334e-49194
NC_013421:3117639:312370331237033124356654Pectobacterium wasabiae WPP163, complete genomeprotein of unknown function DUF5336e-44177
NC_009708:915814:930649930649930918270Yersinia pseudotuberculosis IP 31758 chromosome, complete genomehypothetical protein5e-32137
NC_009708:915814:930920930920931306387Yersinia pseudotuberculosis IP 31758 chromosome, complete genome4e-2098.2
NC_009654:1729159:173941117394111740136726Marinomonas sp. MWYL1, complete genomehypothetical protein2e-1582.4
NC_014532:1191267:121159712115971212307711Halomonas elongata DSM 2581, complete genomeprotein of unknown function DUF5333e-1478.6
NC_013173:953633:987635987635988321687Desulfomicrobium baculatum DSM 4028, complete genomeprotein of unknown function DUF5336e-1270.9