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Query: NC_016512:679688 Propionibacterium acnes TypeIA2 P.acn17 chromosome, complete

Start: 679688, End: 703471, Length: 23784

Host Lineage: Propionibacterium acnes; Propionibacterium; Propionibacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This bacterium is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline. Some other forms of therapy include chemicals that enhance skin removal or slow the production of sebum.

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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_013093:832971*83297185669123721Actinosynnema mirum DSM 43827, complete genome5e-1487.7BLASTN svgBLASTP svg
NC_013851:949973*94997398051930547Allochromatium vinosum DSM 180 chromosome, complete genome2e-1075.8BLASTN svgBLASTP svg
NC_010170:44096834409683443529725615Bordetella petrii, complete genome3e-0971.9BLASTN svgBLASTP svg
NC_014117:442616*44261651580273187Burkholderia sp. CCGE1002 chromosome chromosome 1, complete3e-0661.9BLASTN svgBLASTP svg
NC_015514:3351052*3351052338153030479Cellulomonas fimi ATCC 484 chromosome, complete genome2e-1695.6BLASTN svgBLASTP svg
NC_009480:739395*73939576050021106Clavibacter michiganensis subsp. michiganensis NCPPB 382, complete5e-23117BLASTN svgBLASTP svg
NC_002935:21036772103677212647322797Corynebacterium diphtheriae NCTC 13129, complete genome5e-0867.9BLASTN svgBLASTP svg
NC_010125:33389533389535661922725Gluconacetobacter diazotrophicus PAl 5, complete genome3e-0971.9BLASTN svgBLASTP svg
NC_013174:2455420*2455420249080635387Jonesia denitrificans DSM 20603, complete genome3e-0971.9BLASTN svgBLASTP svg
NC_006087:23261432326143235421928077Leifsonia xyli subsp. xyli str. CTCB07, complete genome3e-0971.9BLASTN svgBLASTP svg
NC_008699:1247423*1247423126898521563Nocardioides sp. JS614, complete genome1e-1179.8BLASTN svgBLASTP svg
NC_014039:70842770842772779219366Propionibacterium acnes SK137 chromosome, complete genome038270BLASTN svgBLASTP svg
NC_014215:22955002295500232183626337Propionibacterium freudenreichii subsp. shermanii CIRM-BIA1,4e-30141BLASTN svgBLASTP svg
NC_012586:42561542561544912923515Rhizobium sp. NGR234 plasmid pNGR234b, complete sequence3e-1591.7BLASTN svgBLASTP svg
NC_012587:71312471312473838525262Rhizobium sp. NGR234, complete genome3e-0971.9BLASTN svgBLASTP svg