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Query: NC_016512:1810625 Propionibacterium acnes TypeIA2 P.acn17 chromosome, complete

Start: 1810625, End: 1831171, Length: 20547

Host Lineage: Propionibacterium acnes; Propionibacterium; Propionibacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This bacterium is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline. Some other forms of therapy include chemicals that enhance skin removal or slow the production of sebum.

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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_015738:62929762929765226722971Eggerthella sp. YY7918, complete genome2e-0661.9BLASTN svgBLASTP svg
NC_019964:18731671873167190103827872Halovivax ruber XH-70, complete genome2e-1385.7BLASTN svgBLASTP svg
NC_010617:19103881910388192887618489Kocuria rhizophila DC2201, complete genome2e-28135BLASTN svgBLASTP svg
NC_012808:157156*15715618609928944Methylobacterium extorquens AM1, complete genome1e-0560BLASTN svgBLASTP svg
NC_014814:43265004326500435109924600Mycobacterium sp. Spyr1 chromosome, complete genome7e-19103BLASTN svgBLASTP svg
NC_008726:17761921776192180185525664Mycobacterium vanbaalenii PYR-1, complete genome1e-1489.7BLASTN svgBLASTP svg
NC_006085:18591911859191188064221452Propionibacterium acnes KPA171202, complete genome019340BLASTN svgBLASTP svg
NC_014039:18132051813205183638923185Propionibacterium acnes SK137 chromosome, complete genome022310BLASTN svgBLASTP svg
NC_008269:86800086800091059942600Rhodococcus sp. RHA1 plasmid pRHL1, complete sequence2e-37165BLASTN svgBLASTP svg