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Query: NC_014039:499233:506762 Propionibacterium acnes SK137 chromosome, complete genome

Start: 506762, End: 506837, Length: 76

Host Lineage: Propionibacterium acnes; Propionibacterium; Propionibacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This bacterium is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016516:463460:47099547099547107076Propionibacterium acnes TypeIA2 P.acn33 chromosome, completetRNA-Thr4e-0650.1
NC_016511:472666:48019848019848027376Propionibacterium acnes TypeIA2 P.acn31 chromosome, completetRNA-Thr4e-0650.1
NC_006085:481231:48876048876048883879Propionibacterium acnes KPA171202, complete genometRNA-Thr4e-0650.1