Pre_GI: BLASTP Hits

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Query: NC_014039:499233:502462 Propionibacterium acnes SK137 chromosome, complete genome

Start: 502462, End: 503214, Length: 753

Host Lineage: Propionibacterium acnes; Propionibacterium; Propionibacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This bacterium is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016516:463460:466695466695467447753Propionibacterium acnes TypeIA2 P.acn33 chromosome, completeprecorrin-6x reductase CbiJ/CobK2e-120431
NC_016511:472666:475898475898476650753Propionibacterium acnes TypeIA2 P.acn31 chromosome, completeprecorrin-6x reductase CbiJ/CobK2e-120431
NC_006085:481231:4844604844604855001041Propionibacterium acnes KPA171202, complete genomeprecorrin-6x reductase3e-120431
NC_021177:4258102:427109542710954271859765Streptomyces fulvissimus DSM 40593, complete genomeCobalt-precorrin-6x reductase2e-22105
NC_016631:2112175:211136921113692112178810Granulicella mallensis MP5ACTX8 chromosome, complete genomeprecorrin-6x reductase9e-21100
NC_003888:3602753:362569536256953626462768Streptomyces coelicolor A3(2), complete genomeprecorrin-6x reductase1e-1790.5
NC_015065:232240:245702245702246478777Acidobacterium sp. MP5ACTX9 plasmid pACIX902, complete sequenceprecorrin-6x reductase7e-1787.8
NC_016801:1255611:125489212548921255623732Corynebacterium diphtheriae C7 (beta) chromosome, complete genomecobalt-precorrin-6x reductase3e-1685.5
NC_016790:1177349:117663011766301177361732Corynebacterium diphtheriae VA01 chromosome, complete genomecobalt-precorrin-6x reductase7e-1684.3
NC_011758:326366:327636327636328388753Methylobacterium chloromethanicum CM4 plasmid pMCHL01, completeprecorrin-6x reductase3e-1478.6
NC_020829:636773:661256661256661984729Pseudomonas denitrificans ATCC 13867, complete genomecobalt-precorrin-6x reductase2e-1375.9
NC_010511:2703684:270593727059372706698762Methylobacterium sp. 4-46 chromosome, complete genomeprecorrin-6x reductase5e-1374.7
NC_008595:2432184:244849224484922449226735Mycobacterium avium 104, complete genomeprecorrin-6x reductase1e-1273.9
NC_012491:1263469:127360112736011274374774Brevibacillus brevis NBRC 100599, complete genomeprecorrin-6x reductase6e-0961.2
NC_021171:415771:421489421489422262774Bacillus sp. 1NLA3E, complete genomeprecorrin-6x reductase7e-0960.8
NC_013892:853366:860330860330861124795Xenorhabdus bovienii SS-2004 chromosome, complete genomecobalt-precorrin-6A reductase1e-0860.5
NC_015690:7518732:752189675218967522681786Paenibacillus mucilaginosus KNP414 chromosome, complete genomeprecorrin-6x reductase3e-0755.5
NC_011026:2624775:264795126479512648730780Chloroherpeton thalassium ATCC 35110, complete genomeprecorrin-6x reductase1e-0653.9
NC_015573:1979202:198286719828671983685819Desulfotomaculum kuznetsovii DSM 6115 chromosome, complete genomeprecorrin-6x reductase3e-0652.4
NC_005126:3485330:349193234919323492717786Photorhabdus luminescens subsp. laumondii TTO1, complete genomeprecorrin-6x reductase5e-0651.6